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    Article

    Anticancer activity of herbal formula Jisilhaebaekgyeji-Tang against human breast cancer cells and its mechanism

    Jisilhaebaekgyeji-Tang (JHG, Zhishi **ebai Guizhi Tang) is a famous traditional herbal medicine described in the Geumgweyoryak (** Gui Yao Lue), an ancient Chinese medical text. JHG is composed of five medicinal...

    Sang Kyu Jeon, Su Mi Park, Jung Yun Ahn, Ok Hyeon Kim in Molecular & Cellular Toxicology (2023)

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    Open Access

    Polypropylene microplastics promote metastatic features in human breast cancer

    Microplastics (MPs) are now a global issue due to increased plastic production and use. Recently, various studies have been performed in response to the human health risk assessment. However, these studies hav...

    Jun Hyung Park, Seungwoo Hong, Ok-Hyeon Kim, Chul-Hong Kim, **ho Kim in Scientific Reports (2023)

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    Article

    3-Hydroxymorphinan protects against hypoxia-induced cell death in primary astrocyte by regulating Ca2+ influx and the glutamate homeostasis

    Hypoxia is a pathological phenomenon of the central nervous system that occurs during ischemia and stroke, leading to brain cell damage. Astrocytes play an important role in maintaining homeostasis in the brai...

    Ok-Hyeon Kim, Gyeong Yun Lee, Kyung Yong Kim in Molecular & Cellular Toxicology (2023)

  4. Article

    Open Access

    Vitamin C for septic shock in previous randomized trials: implications of erroneous dosing, timing, and duration

    Hyun Jung Lee, Ok-Hyeon Kim, Moon Seong Baek, Won-Young Kim in Critical Care (2022)

  5. Article

    Open Access

    Biomechanical forces enhance directed migration and activation of bone marrow-derived dendritic cells

    Mechanical forces are pervasive in the inflammatory site where dendritic cells (DCs) are activated to migrate into draining lymph nodes. For example, fluid shear stress modulates the movement patterns of DCs, ...

    Ji-Hun Kang, Hyun Joo Lee, Ok-Hyeon Kim, Yong Ju Yun, Young-** Seo in Scientific Reports (2021)

  6. Article

    Open Access

    Anti-tumor effects of the ethanolic extract of Trichosanthes kirilowii seeds in colorectal cancer

    Trichosanthis semen, the seeds of Trichosanthes kirilowii Maxim. or Trichosanthes rosthornii Harms, has long been used in Korean medicine to loosen bowels and relieve chronic constipation. Although the fruits and...

    Su Mi Park, Sang Kyu Jeon, Ok Hyeon Kim, Jung Yun Ahn, Chang-Hyun Kim in Chinese Medicine (2019)