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Article
Open AccessMacrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury
Patients who suffer from sepsis typically experience acute lung injury (ALI). Extracellular vesicles (EVs) contain miRNAs, which are potentially involved in ALI. However, strategies to screen more effective EV...
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Article
Experimentally Modelling a Piezoelectric Glued Laminated Plate Energy of Harvester
The effects of glue layers are regarded as the stiffness and dam** of laminated circular plates. An energy harvester consisting of a concentrated mass and a piezoelectric laminated circular plate is investig...
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Article
Glycolytic enzyme PFKL governs lipolysis by promoting lipid droplet–mitochondria tethering to enhance β-oxidation and tumor cell proliferation
Lipid droplet tethering with mitochondria for fatty acid oxidation is critical for tumor cells to counteract energy stress. However, the underlying mechanism remains unclear. Here, we demonstrate that glucose ...
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Article
Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc
Acetate, a precursor of acetyl-CoA, is instrumental in energy production, lipid synthesis and protein acetylation. However, whether acetate reprogrammes tumour metabolism and plays a role in tumour immune evas...
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Article
Carbon emission reduction enabled by informatization construction: an analysis of spatial effects based on China’s experience
The “dual-carbon” objective presents a huge challenge for China and the world, with profound implications for the advancement of China’s eco-friendly economy. Additionally, informatization development has a si...
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Article
Improved outcomes for triple negative breast cancer brain metastases patients after stereotactic radiosurgery and new systemic approaches
Although ongoing studies are assessing the efficacy of new systemic therapies for patients with triple negative breast cancer (TNBC), the overwhelming majority have excluded patients with brain metastases (BM)...
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Article
Plate theory based modeling and analysis of nonlinear piezoelectric composite circular plate energy harvesters
A piezoelectric composite circular plate energy harvester is modeled and analyzed based on a nonlinear plate theory. The harvester consists of a bimorph piezoelectric circular plate and a rigid body. The nonli...
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Article
Open AccessPlastid genome data provide new insights into the dynamic evolution of the tribe Ampelopsideae (Vitaceae)
Ampelopsideae J. Wen & Z.L. Nie is a small-sized tribe of Vitaceae Juss., including ca. 47 species from four genera showing a disjunct distribution worldwide across all the continents except Antarctica. There ...
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Article
Red mud accommodated mesoporous black TiO2 framework with enhanced organic pollutant photodegradation
In this work, black TiO2 (BTiO2) loaded on black red mud (BRM) was successfully prepared with the conversion of Fe2O3 into magnetic Fe3O4 in red mud and the reduction of partial Ti4+ to Ti3+ in TiO2 via the facil...
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Article
Autophagic degradation of MVBs in LSECs promotes Aldosterone induced-HSCs activation
The important role of extracellular vesicles (EVs) in liver fibrosis has been confirmed. However, EVs derived from liver sinusoidal endothelial cells (LSECs) in the activation of hepatic stellate cells (HSCs) ...
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Article
Volumetric growth rate of incidentally found meningiomas on immunotherapy
The expression of PD-L1 in high-grade meningiomas made it a potential target for immunotherapy research in refractory cases. Several prospective studies in this field are still on going. We sought to retrospec...
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Article
Structural Features, Superatomic Properties, and Adsorptions of Zn–Cd Nanoalloy
Zn–Cd alloys are important industrial materials which have attracted much attentions in recent years. But, few reports on Zn–Cd clusters are currently available. An interesting structural feature in previous s...
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Water Linking to Food and Energy
Water, food, and energy resources are critical concerns to achieve the UN 2030 Sustainable Development Goals. However, achieving food, energy, and water security is under increasing pressure due to population and...
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Article
Chromatin architecture of two different strains of Artemisia annua reveals the alterations in interaction and gene expression
The hierarchical architecture of chromatins affects the gene expression level of glandular secreting trichomes and the artemisinin biosynthetic pathway-related genes, consequently bringing on huge differences ...
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Article
Open AccessOccupational Happiness of Civilian Nurses in China: a cross-sectional study
Civilian nurses have gradually become the main body of military nurses. Our study aimed to understand their occupational happiness and its influencing factors.
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Article
Open AccessNonlinear vibrations of a composite circular plate with a rigid body
The influence of weights is usually ignored in the study of nonlinear vibrations of plates. In this paper, the effect of structure weights on the nonlinear vibration of a composite circular plate with a rigid ...
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Article
Open AccessMultiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities
Malignant peripheral nerve sheath tumor (MPNST) is a highly aggressive sarcoma, and a lethal neurofibromatosis type 1-related malignancy, with little progress made on treatment strategies. Here, we apply a mul...
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Article
Theoretical and numerical investigation of micro-textures fabrication by ultrasonic surface rolling process
Surface texturing is a potential approach to achieving excellent surface performance. To realize high precision and efficiency in micro-texturing fabrication, a surface texturing method utilizing an ultrasonic...
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Article
High Loading Start-Up and Rapid Loading Increase of an Anammox UASB Reactor Generate Superior Anammox Granules
Anaerobic ammonium oxidation (anammox) is an innovative biotechnology for high-efficiency and low-cost removal of ammonia nitrogen in wastewater. However, anammox reactors generally started up with low loading...
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Article
Open AccessPositive correlation between hypertensive retinopathy and albuminuria in hypertensive adults
We investigated the association between albuminuria and hypertensive retinopathy (HR) in hypertensive adults.
