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Article
Role and recent progress of P2Y12 receptor in cancer development
P2Y12 receptor (P2Y12R) is an adenosine-activated G protein-coupled receptor (GPCR) that plays a central role in platelet function, hemostasis, and thrombosis. P2Y12R activation can promote platelet aggregatio...
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Article
Divergent intra- and interspecific root order variability identifies a two-dimensional root economics spectrum
The form-function linkages and variation of fine root traits reflect adaptive strategies to cope with complex soil environments. However, their contributions to the root economics spectrum (RES) remain unclear.
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Article
Open AccessTargeting SOX13 inhibits assembly of respiratory chain supercomplexes to overcome ferroptosis resistance in gastric cancer
Therapeutic resistance represents a bottleneck to treatment in advanced gastric cancer (GC). Ferroptosis is an iron-dependent form of non-apoptotic cell death and is associated with anti-cancer therapeutic eff...
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Article
How does the development of the digital economy influence carbon productivity? The moderating effect of environmental regulation
Improving carbon productivity is of great significance to China’s “30 · 60” carbon target, while the development of the digital economy is a driving force for green transformation. However, few studies discuss...
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Article
Investigation of the Influence of Operating Parameters on the Settling Performance of a Vertical Sedimentation Tank Through Computational Fluid Dynamics Simulations
The operating conditions of the sedimentation tanks are very critical for wastewater treatment. The effects of operating parameters (inlet velocity, inlet sludge concentration and reflux ratio) on the settling...
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Article
Open AccessBlockade of C5aR1 resets M1 via gut microbiota-mediated PFKM stabilization in a TLR5-dependent manner
Targeting C5aR1 modulates the function of infiltrated immune cells including tumor-associated macrophages (TAMs). The gut microbiome plays a pivotal role in colorectal cancer (CRC) tumorigenesis and developmen...
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Article
Open AccessDiphylleia Grayi-Inspired Intelligent Temperature-Responsive Transparent Nanofiber Membranes
Temperature-responsive transparent nanofiber membranes were successfully fabricated using a straightforward and widely applicable method.
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Article
Temperature dependence of carbon metabolism in the leaves in sun and shade in a subtropical forest
Rising temperatures pose a threat to the stability of climate regulation by carbon metabolism in subtropical forests. Although the effects of temperature on leaf carbon metabolism traits in sun-exposed leaves ...
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Article
The allocation of anatomical traits determines the trade-off between fine root resource acquisition–transport function
Cortex radius (CR) and stele radius (SR) are important functional traits associated with the nutrient acquisition and transport functions of fine roots, respectively. However, for developmental and anatomical ...
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Article
Open AccessHigher CD4+CD40+ T cells (Th40 cells) associate with systemic lupus erythematosus activity
The aim of this study was to investigate the characteristics of CD4+CD40+ T cells (Th40 cells) in Chinese systemic lupus erythematosus (SLE) patients. Flow cytometry was used to identify the percentage of Th40 ce...
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Article
Open AccessThe cross-sectional area ratio of a specific part of the flexor pollicis longus tendon- a stable sonographic measurement for trigger thumb: a cross-sectional trial
Trigger thumb is a pathologic condition of the digital pulleys and flexor tendons. To find a cutoff value of the cross-sectional area ratio of specific parts of the flexor pollicis longus tendon to diagnosis t...
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Article
Adsorption of methylene blue on activated carbons prepared from penicillin mycelial residues via torrefaction and hydrothermal pretreatment
In this study, the effects of torrefaction (TF) and hydrothermal treatment (HT) on the preparation of activated carbons (ACs) from penicillin mycelia residues (PMR) were investigated. Textural properties, micr...
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Article
Does nitrogen fertilization alter the scaling relationships of multinutrients in tree organs? Evidence from Chinese hickory (Carya cathayensis) saplings
Nitrogen (N) enrichment from excessive fertilization influences the coupling of nutrients in terrestrial ecosystems, but whether it could alter the scaling relationships between multinutrients [including macro...
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Article
Open AccessAssociation of frailty with the incidence risk of cardiovascular disease and type 2 diabetes mellitus in long-term cancer survivors: a prospective cohort study
Comorbidities among cancer survivors remain a serious healthcare burden and require appropriate management. Using two widely used frailty indicators, this study aimed to evaluate whether frailty was associated...
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Article
Open AccessCancer functional states-based molecular subtypes of gastric cancer
The treatment of gastric cancer remains a challenge.
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Article
Open AccessLncRNA AK089514/miR-125b-5p/TRAF6 axis mediates macrophage polarization in allergic asthma
Micro RNA (miRNA) plays important roles in macrophage polarization. However, the manner in which miRNA regulate macrophage polarization in response to dermatophagoides farinae protein 1(Der f1)-induced asthma ...
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Article
Construction of amphiphilic networks in blend membranes for CO2 separation
Blend membranes have attracted great attention because they can combine the advantages of different polymers. To investigate the effect of amphiphilic polymer on the separation performance of blend membranes, ...
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Article
Brush-electroplated rGO@MnO2 composite supported on carbon cloth for flexible high-performance supercapacitor electrodes
With the emergence of intelligent society, high energy density and safety of flexible capacitive energy storage units are increasingly important in wearable devices. MnO2 as a flexible supercapacitor electrode ma...
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Article
Novel Synthesis and Characterization of Flexible MnO2/CNT Composites Co-deposited on Graphite Paper as Supercapacitor Electrodes
Although MnO2 possesses many advantages, such as a high theoretical specific capacity, resource abundance, easy synthesis and environmental friendliness, its poor electrical conductivity and low utilization serio...
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Article
Tailoring physical and chemical microenvironments by polyether-amine in blended membranes for efficient CO2 separation
Pebax® MH 1657 (Pebax)-based blend membranes with different polyether-amine (PEA) loadings were designed and fabricated for efficient CO2 separation. The CO2 separation performance of Pebax/PEA blend membranes wa...
