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Article
FEZF2 inhibits the growth of triple-negative breast cancer cells through EZH2/PD-L1 and enhances anti-tumor immunity in vivo
Triple-negative breast cancer (TNBC) is characterized by high aggressiveness, heterogeneity, and poor prognosis. Programmed cell death 1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors, a crucial type of i...
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Article
Fe3O4 nanoparticles encapsulated in graphitized and in-plane porous carbon nanocages derived from emulsified asphalt for a high-performance lithium-ion battery anode
In this work, C@Fe3O4 composites were prepared through a typical template method with emulsified asphalt as carbon source, ammonium ferric citrate as transition metal oxide precursor, and NaCl as template. As an ...
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Article
Divergent intra- and interspecific root order variability identifies a two-dimensional root economics spectrum
The form-function linkages and variation of fine root traits reflect adaptive strategies to cope with complex soil environments. However, their contributions to the root economics spectrum (RES) remain unclear.
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Article
Open AccessIdentification of neurological complications in childhood influenza: a random forest model
Among the neurological complications of influenza in children, the most severe is acute necrotizing encephalopathy (ANE), with a high mortality rate and neurological sequelae. ANE is characterized by rapid pro...
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Article
Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening
T cell receptor (TCR) gene therapy is a potent form of cellular immunotherapy in which patient T cells are genetically engineered to express TCRs with defined tumor reactivity. However, the isolation of therap...
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Article
An extended sparse model for blind image deblurring
Blind image deblurring is a classical ill-posed problem that usually requires constraints on the clean image, the blur kernel, and noise to make it well-posed. Recently, a simple yet effective sparse norm ...
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Article
Open AccessAdvancements in understanding chicken coccidiosis: from Eimeria biology to innovative control strategies
Coccidiosis, an intestinal disease caused by Eimeria protozoan parasites, affects various animal species, and especially poses a significant threat to the poultry industry. The current primary control methods inc...
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Article
Temperature dependence of carbon metabolism in the leaves in sun and shade in a subtropical forest
Rising temperatures pose a threat to the stability of climate regulation by carbon metabolism in subtropical forests. Although the effects of temperature on leaf carbon metabolism traits in sun-exposed leaves ...
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Article
Open AccessMitochondrial dysfunction induced by bedaquiline as an anti-Toxoplasma alternative
Toxoplasma gondii is a zoonotic parasite that infects one-third of the world’s population and nearly all warm-blooded animals. Due to the complexity of T. gondii’s life cycle, available treatment options have lim...
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Article
Seroprevalence of Toxoplasma gondii in water buffaloes and cats in Guangxi, China
Toxoplasma gondii is a pathogen that poses a serious threat to human health and causes significant economic losses to the global livestock industry. The prevalence of toxoplasmosis infection has been reported to ...
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Article
Survival benefit and impact of adjuvant therapies following FOLFOX-HAIC-based conversion therapy with unresectable hepatocellular carcinoma: a retrospective cohort study
Recently, the conversion therapies of FOLFOX-HAIC for patients with unresectable hepatocellular carcinoma (uHCC) have dramatically increased the tumor responses and conversion rate; thus, the prognosis of uHCC...
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Article
Open AccessDistinct non-synonymous mutations in cytochrome b highly correlate with decoquinate resistance in apicomplexan parasite Eimeria tenella
Protozoan parasites of the genus Eimeria are the causative agents of chicken coccidiosis. Parasite resistance to most anticoccidial drugs is one of the major challenges to controlling this disease. There is an ur...
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Article
Blind Image Deblurring via Weighted Dark Channel Prior
Blind image deblurring is a challenging problem, which aims to estimate the blur kernel and recover the clear image from the given blurry image. A large number of image priors have been proposed to tackle this...
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Article
Adaptive diagonal matrix compensation matrix based virtual synchronous generator power decoupling control strategy
This paper discusses the power coupling problem of the traditional virtual synchronous generator (VSG) control strategy in medium and low-voltage microgrids, analyzes the cause of power coupling, and discusses...
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Article
The allocation of anatomical traits determines the trade-off between fine root resource acquisition–transport function
Cortex radius (CR) and stele radius (SR) are important functional traits associated with the nutrient acquisition and transport functions of fine roots, respectively. However, for developmental and anatomical ...
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Article
Open AccessComparative transcriptome profiling of Eimeria tenella in various developmental stages and functional analysis of an ApiAP2 transcription factor exclusively expressed during sporogony
The apicomplexan parasites Eimeria spp. are the causative agents of coccidiosis, a disease with a significant global impact on the poultry industry. The complex life cycle of Eimeria spp. involves exogenous (spor...
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Article
Image Deconvolution Using Mixed-Order Salient Edge Selection
Salient edge selection is a crucial technique to warrant the success of image deblurring. Current edge-based methods mainly focus on the single salient edge without exploiting the rich structural information o...
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Article
Open AccessMg-incorporated micro/nano-topographical calcium silicate coatings with enhanced osteogenic properties and reduced inflammatory reactions
Orthopedic implant coatings with optimized surface topography and chemistry can achieve favorable osteogenesis and inflammatory responses. In this work, to take advantage of micro/nano-topography and nutrient ...
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Article
The combination treatment strategy of lenvatinib for hepatocellular carcinoma: a real-world study
Lenvatinib is recommended as a first-line therapy in unresectable hepatocellular carcinoma (HCC). Combination therapy with local therapy (LT) or PD-1/PD-L1 inhibitors (PI) might improve the antitumor effect of...
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Article
Xenogeneic collagen matrix versus free gingival graft for augmenting keratinized mucosa around posterior mandibular implants: a randomized clinical trial
To assess the clinical efficacy of xenogeneic collagen matrix (XCM) plus apically positioned flap (APF) in augmenting the keratinized mucosa (KM) width (KMW) and thickness (KMT) around posterior mandibular imp...
