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Article
PCDH11X mutation as a potential biomarker for immune checkpoint therapies in lung adenocarcinoma
Immune checkpoint inhibitors (ICIs) have achieved impressive success in lung adenocarcinoma (LUAD). However, the response to ICIs varies among patients, and predictive biomarkers are urgently needed. PCDH11X is f...
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Article
Developmental validation of the STRSeqTyper122 kit for massively parallel sequencing of forensic STRs
Massively parallel sequencing allows for integrated genoty** of different types of forensic markers, which reduces DNA consumption, simplifies experimental processes, and provides additional sequence-based g...
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Article
Association between stress hyperglycemia ratio with short-term and long-term mortality in critically ill patients with ischemic stroke
Hyperglycemia on admission is associated with poor prognosis in ischemic stroke (IS) patients. We aimed to investigate the relationship between stress hyperglycemia ratio (SHR) and short-term or long-term mort...
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Article
Open AccessAssociation of the stress hyperglycemia ratio with coronary artery disease complexity as assessed by the SYNTAX score in patients with acute coronary syndrome
Mounting evidence supports a significant correlation between the stress hyperglycemia ratio (SHR) and both short- and long-term prognoses in patients with acute coronary syndrome (ACS). Nevertheless, research ...
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Article
Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
Sympathetic eruptions of solar prominences have been studied for decades, however, it is usually difficult to identify their causal links. Here, we present two failed prominence eruptions on 26 October 2022 an...
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Article
Open AccessRotation with other crops slow down the fungal process in tobacco-growing soil
Continuous cultivation of tobacco could cause serious soil health problems, which could cause bacterial soil to change to fungal soil. In order to study the diversity and richness of fungal community in tobacc...
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Article
Open AccessDevelopment and validation of a risk prediction model for invasiveness of pure ground-glass nodules based on a systematic review and meta-analysis
Assessing the aggressiveness of pure ground glass nodules early on significantly aids in making informed clinical decisions.
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Article
Upadacitinib for axial spondyloarthritis: a meta-analysis of efficacy and safety
To explore the effectiveness and safety of upadacitinib for managing axial spondyloarthritis. Four databases (PubMed, EMBASE, Cochrane, and Web of Science) were applied to search randomized controlled trials (...
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Article
Open AccessApplication of Artificial Intelligence Technology in Vulnerability Analysis of Intelligent Ship Network
The improvement in transportation efficiency, security, safety, and environmental effects may be possible due to the impending advent of autonomous ships. Automatic situational awareness, risk detection, and i...
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Article
Open AccessPharmacokinetics, Safety, and Immunogenicity of Intravenous and Subcutaneous Single-Dose QX002N Injection in Healthy Subjects: A Randomized, Open, Parallel, Single-Center, Phase I Study
Interleukin-17A (IL-17A) plays a crucial role in the pathogenesis of ankylosing spondylitis (AS), although not all patients respond to traditional IL-17A antibody treatments. QX002N injection, as a new monoclo...
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Article
Three-way concept lattices triggered by Pythagorean fuzzy set and interval set
Three-way concept lattices offer a robust and flexible framework for analyzing complex data and understanding relationships and patterns within datasets. Their ability to handle uncertainty and ambiguity makes...
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Article
Open AccessSurvival benefits of postoperative radiotherapy in patients with cT1 − 2N1M0 breast cancer after neoadjuvant chemotherapy: a SEER-based population study
Whether patients with cT1 − 2N1M0 breast cancer can benefit from postoperative radiotherapy (RT) after receiving neoadjuvant chemotherapy (NAC) has been controversial. Therefore, the purpose of this study was to ...
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Article
A blockchain-based auditable deduplication scheme for multi-cloud storage
Cloud storage has attracted widespread attention due to its advantages such as convenience, low cost, and easy scalability. With the explosion of cloud data volumes, security and performance issues are becomin...
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Article
Sustainable utilization of residual grass: effect of anaerobic storage days on chemical composition, fermentation performance, microbial community, and functional profiles of Pennisetum giganteum
The seasonal surplus and putrefactive property of moist forages inevitably increase the pressure on environmental protection and residual grass disposal. In the current work, the anaerobic fermentation approac...
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Article
Peanut straw application rate had a greater effect on decomposition and nitrogen, potassium and phosphorus release than irrigation
Peanut (Arachis hypogaea L.) straw decomposition and nutrient release (N, K, and P) processes were investigated using a 3-pool model (labile, intermediate, and resistant) to understand the determinant factors.
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Article
Quantifying the role of insurance in tornado-impacted community recovery: a survey and simulation-based approach
Insurance against disasters plays a critical role in community recovery by providing policyholders with reliable and timely payments for repairing or reconstructing damaged houses. By allowing homeowners to tr...
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Article
Open AccessBright X/ \(\gamma\) -ray emission and lepton pair production by strong laser fields: a review
The advent of high-power ultra-short laser pulses opens up new frontiers of relativistic non-linear optics, high energy density physics and laboratory astrophysics. As the laser electric field in the particle ...
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Article
Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis
Sphingomyelin (SM) has key roles in modulating mammalian membrane properties and serves as an important pool for bioactive molecules. SM biosynthesis is mediated by the sphingomyelin synthase (SMS) family, com...
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Article
Effects of fuel and driving conditions on particle number emissions of China-VI gasoline vehicles: based on corrections to test results
The increasing number of vehicles are emitting a large amount of particles into the atmosphere, causing serious harm to the ecological environment and human health. This study conducted the Worldwide Harmonize...
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Article
Open AccessAutomatic Solar Flare Detection Using the Solar Disk Imager Onboard the ASO-S Mission
We present an automated solar flare detection software tool to automatically process solar observed images, detect and track solar flares, and finally compile an event catalog. It can identify and track flares...
