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Article
Ultrasound-based radiomics nomogram for predicting axillary lymph node metastasis in early-stage breast cancer
We aimed at assessing the predictive ability of ultrasound-based radiomics combined with clinical characteristics for axillary lymph node (ALN) status in early-stage breast cancer patients and to compare perfo...
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Article
Open AccessCrowdfunding innovative but risky new ventures: the importance of less ambiguous tone
Crowdfunding provides a novel and potential way for innovative but risky new ventures to fund their new product development (NPD) projects. To help potential investors evaluate the projects and enhance the cre...
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Article
Combining serum AFP and CEUS LI-RADS for better diagnostic performance in Chinese high-risk patients
To evaluate and compare the diagnostic performance of revised contrast-enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System version by combining LR-M category and serum alpha-fetoprotein (AFP) un...
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Article
Order Timing for Manufacturers with Spot Purchasing Price Uncertainty and Demand Information Updating
In this paper we study the competitive order timing decisions of two manufacturers with demand forecasting updating and uncertain raw material price. Manufacturers can order the raw materials early when the ma...
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Article
Mismatch risk allocation in a coproduct supply chain
Products such as cattles and pigs can be processed into several types of products (parts) targeting different segments of customers, which belong to the so called coproducts. Mismatch risk is a significant issue ...
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Article
Open AccessHistone methyltransferase G9a protects against acute liver injury through GSTP1
Acute liver injury is commonly caused by bacterial endotoxin/lipopolysaccharide (LPS), and by drug overdose such as acetaminophen (APAP). The exact role of epigenetic modification in acute liver injury remains...
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Article
Open AccessRecurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma
Natural killer/T cell lymphoma (NKTCL) is a rare and aggressive malignancy with a higher prevalence in Asia and South America. However, the molecular genetic mechanisms underlying NKTCL remain unclear. Here, w...
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Article
Open AccessRecurrent PDGFRB mutations in unicentric Castleman disease
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Article
Open AccessANGPTL8 negatively regulates NF-κB activation by facilitating selective autophagic degradation of IKKγ
Excessive nuclear factor-κB (NF-κB) activation mediated by tumor necrosis factor α (TNFα) plays a critical role in inflammation. Here we demonstrate that angiopoietin-like 8 (ANGPTL8) functions as a negative f...
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Article
Effect of rituximab on primary central nervous system lymphoma: a meta-analysis
The effect of rituximab on primary central nervous system lymphoma (PCNSL) is controversial. We performed this meta-analysis to assess the efficacy of treatment with or without rituximab for PCNSL. We first co...
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Article
Analysis of market competition and information asymmetry on selling strategies
In this paper, we consider the seller’s selling strategies in a supply chain consisting of one supplier and multiple retailers, who compete in the same consumer market. The production lead time is relatively l...
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Article
Restoration of Opa1-long isoform inhibits retinal injury-induced neurodegeneration
Optic atrophy 1 (Opa1) is a critical factor that regulates fusion and other important functions of mitochondria. In mitochondrion, the N-terminal mitochondrial targeting sequence of Opa1 precursors is removed ...
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Article
Loss-averse newsvendor problem with supply risk
Modeling the manufacturer as a newsvendor, in this paper we study the ordering decisions of a loss-averse newsvendor with supply and demand uncertainties. Using the stylized newsvendor models, we analyse sever...
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Article
Optimal policy with a total order quantity commitment contract in the presence of a spot market
In this paper, the optimal policy is considered when the buyer faces two supply sources: one is the contract supplier from which the buyer orders over a specific contract period (say, a year) at a pre-agreed p...