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  1. Article

    Open Access

    Long-term outcomes after particle radiation therapy in patients with nasopharyngeal adenoid cystic carcinoma

    Nasopharyngeal adenoid cystic carcinoma (NACC) is a relatively rare salivary gland tumor that is generally associated with poor outcomes. High-dose radiotherapy is a key treatment for patients with NACC. This ...

    Weixu Hu, Jiyi Hu, Qingting Huang, **g Gao, Haojiong Zhang, Lin Kong in BMC Cancer (2024)

  2. Article

    Open Access

    High-frame-rate contrast-enhanced ultrasound to differentiate between clear cell renal cell carcinoma and angiomyolipoma

    To investigate the diagnostic efficacy of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in differentiating between clear cell renal cell carcinoma (CCRCC) and angiomyolipoma (AML).

    **gLing Wang, JiaYu Shi, Long Gao, WeiHong Hu, Miao Chen, Wei** Zhang in BMC Cancer (2024)

  3. Article

    Open Access

    Age at lung cancer diagnosis in females versus males who never smoke by race and ethnicity

    We characterized age at diagnosis and estimated sex differences for lung cancer and its histological subtypes among individuals who never smoke.

    Batel Blechter, Jason Y. Y. Wong, Li-Hsin Chien in British Journal of Cancer (2024)

  4. Article

    Open Access

    Correction: CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer

    Hongbao Yang, **aobo Li, Qingtao Meng, Hao Sun, Shenshen Wu, Weiwei Hu in Molecular Cancer (2024)

  5. Article

    Open Access

    SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53

    Bladder cancer (BCa) is one of the most common malignancies worldwide. However, the lack of accurate and effective targeted drugs has become a major problem in current clinical treatment of BCa. Studies have d...

    Fan Zou, Wu Chen, Tianbao Song, Ji **ng, Yunlong Zhang in Cancer Cell International (2023)

  6. Article

    Open Access

    The prognostic role of coagulation markers in the progression and metastasis of laryngeal squamous cell carcinoma

    The application of coagulation-related markers in laryngeal squamous cell carcinoma(LSCC) remains unclear. This study explored the prognostic role of coagulation markers in the progression and metastasis of LSCC.

    Qiongling Huang, **g Chen, Yanjun Huang, Yu **ong, Jiao Zhou, Yizheng Zhang in BMC Cancer (2023)

  7. No Access

    Article

    The efficacy and safety of low-intensity extracorporeal shock wave treatment combined with or without medications in Chronic prostatitis/chronic pelvic pain syndrome: a systematic review and meta-analysis

    We performed this systematic review and meta-analysis to investigate the efficacy and safety of Li-ESWT combined with or without medications for patients with Chronic prostatitis/Chronic Pelvic Pain Syndrome (...

    **angbin Kong, Weiwei Hu, Zhilong Dong in Prostate Cancer and Prostatic Diseases (2023)

  8. Article

    Open Access

    The screening, identification, design and clinical application of tumor-specific neoantigens for TCR-T cells

    Recent advances in neoantigen research have accelerated the development of tumor immunotherapies, including adoptive cell therapies (ACTs), cancer vaccines and antibody-based therapies, particularly for solid ...

    Jiang** Li, Zhiwen **ao, Donghui Wang, Lei Jia, Shihong Nie in Molecular Cancer (2023)

  9. Article

    Open Access

    Correction: FOXC1-mediated LINC00301 facilitates tumor progression and triggers an immune-suppressing microenvironment in non-small cell lung cancer by regulating the HIF1α pathway

    Cheng-Cao Sun, Wei Zhu, Shu-Jun Li, Wei Hu, Jian Zhang, Yue Zhuo in Genome Medicine (2023)

  10. No Access

    Article

    Hepatitis B virus X protein promotes MAN1B1 expression by enhancing stability of GRP78 via TRIM25 to facilitate hepatocarcinogenesis

    GRP78 has been implicated in hepatocarcinogenesis. However, the clinical relevance, biological functions and related regulatory mechanisms of GRP78 in hepatitis B virus (HBV)-associated hepatoma carcinoma (HCC...

    Hongjuan You, Ning Zhang, Tong Yu, Lihong Ma, Qi Li, **ng Wang in British Journal of Cancer (2023)

  11. Article

    Open Access

    Multi-omics analyses of CD276 in pan-cancer reveals its clinical prognostic value in glioblastoma and other major cancer types

    CD276 (also known as B7-H3) is one of the most important immune checkpoints of the CD28 and B7 superfamily, and its abnormal expression is closely associated with various types of cancer. It has been shown that C...

    Lirui Dai, Xuyang Guo, Zhe **ng, Yiran Tao, Wulong Liang, Zimin Shi in BMC Cancer (2023)

  12. Article

    Open Access

    Evaluation of a hybrid automatic planning solution for rectal cancer

    Script-based planning and knowledge-based planning are two kinds of automatic planning solutions. Hybrid automatic planning may integrate the advantages of both solutions and provide a more robust automatic pl...

    Jiyou Peng, Lei Yu, Fan **a, Kang Zhang, Zhen Zhang, Jiazhou Wang in Radiation Oncology (2022)

  13. Article

    Open Access

    Correction: CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-IRNA-editing

    Peng Shen, Taoyue Yang, Qun Chen, Hao Yuan, Pengfei Wu, Baobao Cai in Molecular Cancer (2022)

  14. Article

    Open Access

    HLX11, a Proposed Pertuzumab Biosimilar: Pharmacokinetics, Immunogenicity, and Safety Profiles Compared to Three Reference Biologic Products (US-, EU-, and CN-Approved Pertuzumab) Administered to Healthy Male Subjects

    Pertuzumab is a humanized monoclonal antibody for the treatment of breast cancer. HLX11 is a biosimilar of pertuzumab developed by Shanghai Henlius Biotech, Inc. We conducted a bioequivalence study for HLX11 a...

    **g**g Yang, Lili Lin, Qihe Long, Qian Zhang, Guilan Sun, Liang Zhou in BioDrugs (2022)

  15. Article

    Open Access

    SRTdb: an omnibus for human tissue and cancer-specific RNA transcripts

    The production of functional mature RNA transcripts from genes undergoes various pre-transcriptional regulation and post-transcriptional modifications. Accumulating studies demonstrated that gene transcription...

    Qili Shi, Teng Liu, Wei Hu, Zhiao Chen, **anghuo He, Shengli Li in Biomarker Research (2022)

  16. Article

    Open Access

    A multicenter noninferior randomized controlled study comparing the efficacy of laparoscopic versus abdominal radical hysterectomy for cervical cancer (stage IA1 with LVSI, IA2): study protocol of the LAUNCH 1 trial

    A retrospective study and a randomized controlled trial published in a high quality journal in late 2018 have shown that laparoscopic radical hysterectomy (RH) was associated with worse survival than abdominal...

    **n Wu, Hao Feng, Shujun Gao, Hua Feng, Wen**g Diao, Hongwei Zhang, Ming Du in BMC Cancer (2022)

  17. Article

    Open Access

    A novel prognostic cancer-related lncRNA signature in papillary renal cell carcinoma

    Papillary renal cell carcinoma (pRCC) ranks second in renal cell carcinoma and the prognosis of pRCC remains poor. Here, we aimed to screen and identify a novel prognostic cancer-related lncRNA signature in pRCC.

    Binghai Chen, Di Dong, Qin Yao, Yuanzhang Zou, Wei Hu in Cancer Cell International (2021)

  18. Article

    Open Access

    Insights into homeobox B9: a propeller for metastasis in dormant prostate cancer progenitor cells

    Metastasis is the major cause of treatment failure and cancer-related deaths in prostate cancer (PCa) patients. Our previous study demonstrated that a CD44+ subpopulation isolated from PCa cells or tumours posses...

    Yi Sui, Wei Hu, Wei Zhang, Dejian Li, Hongbo Zhu, Qinghua You in British Journal of Cancer (2021)

  19. Article

    Open Access

    FUS-induced circRHOBTB3 facilitates cell proliferation via miR-600/NACC1 mediated autophagy response in pancreatic ductal adenocarcinoma

    Circular RNAs (circRNAs) are becoming a unique member of non-coding RNAs (ncRNAs) with emerging evidence of their regulatory roles in various cancers. However, with regards to pancreatic ductal adenocarcinoma ...

    Taoyue Yang, Peng Shen, Qun Chen, Pengfei Wu in Journal of Experimental & Clinical Cancer … (2021)

  20. Article

    Open Access

    Statins: a repurposed drug to fight cancer

    As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol and improve cardiovascular risk, but also exhibit pleiotropic effects that are independent of their lipid-lowering effec...

    Wen Jiang, **-Wei Hu, Xu-Ran He in Journal of Experimental & Clinical Cancer … (2021)

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