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Article
Dissecting the networks underlying diverse brain disorders after prenatal glucocorticoid overexposure
New human life begins in the uterus in a period of both extreme plasticity and sensitivity to environmental disturbances. The fetal stage is also a vital period for central nervous system development, with exp...
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Article
Open AccessDevelopment of an HSV-1 production process involving serum-reduced culturing and bead-to-bead transfer
Herpes simplex virus type 1 (HSV-1) plays an important role in the field of gene therapy and viral vaccines, especially as an oncolytic virus. However, the mass production of HSV-1 viral vectors remains a chal...
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Article
Open AccessHigh-dimensional mediation analysis for continuous outcome with confounders using overlap weighting method in observational epigenetic study
Mediation analysis is a powerful tool to identify factors mediating the causal pathway of exposure to health outcomes. Mediation analysis has been extended to study a large number of potential mediators in hig...
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Article
Open AccessStress-induced epinephrine promotes hepatocellular carcinoma progression via the USP10-PLAGL2 signaling loop
Hepatocellular carcinoma (HCC) is associated with a poor prognosis. Our previous study demonstrated that Pleomorphic adenoma gene like-2 (PLAGL2) was a potential therapeutic target in HCC. However, the mechani...
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Article
Insights Into Formation and Aging of Secondary Organic Aerosol From Oxidation Flow Reactors: A Review
This review aims to provide a comprehensive examination of oxidation flow reactor (OFR) studies and their applications in both laboratory and field investigations. OFRs play a crucial role in understanding sec...
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Article
Open AccessClinical features, treatment, and follow-up of OPPG and high-bone-mass disorders: LRP5 is a key regulator of bone mass
Osteoporosis-pseudoglioma syndrome (OPPG) and LRP5 high bone mass (LRP5-HBM) are two rare bone diseases with opposite clinical symptoms caused by loss-of-function and gain-of-function mutations in LRP5. Bisphosph...
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Article
Open AccessOutlier detection in spatial error models using modified thresholding-based iterative procedure for outlier detection approach
Outliers, data points that significantly deviate from the norm, can have a substantial impact on statistical inference and provide valuable insights in data analysis. Multiple methods have been developed for o...
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Article
Optimal Control for Suppression of Singularity in Chemotaxis via Flow Advection
This work focuses on the optimal control design for suppressing the singularity formation in chemotaxis governed by the parabolic-elliptic Patlak–Keller–Segel (PKS) system via flow advection. The main idea of ...
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Article
Open AccessCorrection: CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer
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Article
Two-mobile anchor node-based localization in wireless sensor networks
Localization is a fundamental issue in wireless sensor networks (WSNs). Localization with mobile anchors is one of the most efficient ways to deploy sensor nodes and locate them. Due to the limitations of cost...
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Article
Clone-comb-enabled high-capacity digital-analogue fronthaul with high-order modulation formats
Access to the internet by mobile terminals relies on the transmission of information from the optical fibre backbone to wireless networks. Fronthaul, as the last mile of fibre-wireless convergence, determines ...
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Article
The efficacy and safety of low-intensity extracorporeal shock wave treatment combined with or without medications in Chronic prostatitis/chronic pelvic pain syndrome: a systematic review and meta-analysis
We performed this systematic review and meta-analysis to investigate the efficacy and safety of Li-ESWT combined with or without medications for patients with Chronic prostatitis/Chronic Pelvic Pain Syndrome (...
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Article
Open AccessExcitatory somatostatin interneurons in the dentate gyrus drive a widespread seizure network in cortical dysplasia
Seizures due to cortical dysplasia are notorious for their poor prognosis even with medications and surgery, likely due to the widespread seizure network. Previous studies have primarily focused on the disrupt...
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Article
Evaluation of malnutrition and inflammation after total parathyroidectomy in patients on maintenance dialysis
To evaluate the effect of total parathyroidectomy (tPTx) on malnutrition and inflammation in patients on maintenance dialysis (MHD) having secondary hyperparathyroidism (SHPT).
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Article
Open AccessMicrocomb-based integrated photonic processing unit
The emergence of parallel convolution-operation technology has substantially powered the complexity and functionality of optical neural networks (ONN) by harnessing the dimension of optical wavelength. However...
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Chapter and Conference Paper
Analysis on the Global Competition of Digital Reactor from the Perspective of Patents
In recent years, with the rapid development of high-precision reactor simulation, big data applications and high-speed data transmission technologies, countries around the world have rushed to introduce strate...
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Article
Open AccessRetraction Note: Research on image correction method of network education assignment based on wavelet transform
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Article
Effect of chronic stress on tumorigenesis and development
Chronic stress activates the sympathetic nervous system (SNS) and hypothalamic–pituitary–adrenal (HPA) axis to aggravates tumorigenesis and development. Although the importance of SNS and HPA in maintaining ho...
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Article
Bilinear Control of Convection-Cooling: From Open-Loop to Closed-Loop
This paper is concerned with a bilinear control problem for enhancing convection-cooling via an incompressible velocity field. Both optimal open-loop control and closed-loop feedback control designs are addres...
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Article
Open AccessThe relationship between ambulatory arterial stiffness index and left ventricular diastolic dysfunction in HFpEF: a prospective observational study
The relationship between ambulatory arterial stiffness index (AASI) and left ventricular diastolic dysfunction (LVDD) in patients with heart failure with preserved ejection fraction (HFpEF) is unknown. We aime...
