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Article
Open AccessGenome-wide identification and structural analysis of the BMP gene family in Triplophysa dalaica
Bone morphogenetic proteins (BMPs) are part of the transforming growth factor beta (TGF-β) superfamily and play crucial roles in bone development, as well as in the formation and maintenance of various organs. Tr...
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Article
Open AccessGINv2.0: a comprehensive topological network integrating molecular interactions from multiple knowledge bases
Knowledge bases have been instrumental in advancing biological research, facilitating pathway analysis and data visualization, which are now widely employed in the scientific community. Despite the establishme...
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Chapter and Conference Paper
Research on Stress Measurement Method Based on Acoustic Microscopy System
In this paper, a method for stress measurement of semi-infinite structural is presented based on line-focus acoustic microscopy. Based on the acoustoelastic theory and the superposition of partial bulk wave (S...
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Article
Open AccessCorrelation between preoperative peripheral blood NLR, PLR, LMR and prognosis of patients with head and neck squamous cell carcinoma
Markers that can be used to evaluate the prognosis of patients with head and neck squamous cell carcinoma (HNSCC) remain undefined.
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Article
Open AccessTargeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer
Ferroptosis is a new type of iron-dependent programmed cell death induced by lipid peroxidation. However, the underlying mechanisms and function in tumor therapy still remain undisclosed especially in post-tra...
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Article
Open AccessIntelligent Recognition Using Ultralight Multifunctional Nano-Layered Carbon Aerogel Sensors with Human-Like Tactile Perception
The tactile performance of ultralight multifunctional sensors can reach the level of human tactile perception.
An individual...
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Article
Open AccessThe prognostic role of coagulation markers in the progression and metastasis of laryngeal squamous cell carcinoma
The application of coagulation-related markers in laryngeal squamous cell carcinoma(LSCC) remains unclear. This study explored the prognostic role of coagulation markers in the progression and metastasis of LSCC.
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Article
Open AccessFYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancer
FYN is a nonreceptor tyrosine kinase that regulates diverse pathological processes. The pro-cancer role of FYN in multiple malignancies has been elucidated. However, the mechanisms that FYN promotes gastric ca...
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Article
Open AccessPrognostic impact of lymphovascular and perineural invasion in squamous cell carcinoma of the tongue
This study aimed to investigate the prognostic impact of lymphovascular and perineural invasions in patients with squamous cell carcinoma of the tongue who received surgery-based treatment at our institution b...
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Article
Sandwich-type electrochemical immunosensing of hypopharyngeal carcinoma biomarker carcinoembryonic antigen based on N-doped hollow mesoporous nanocarbon spheres/gold hybrids as sensing platform and gold/ferrocene as signal amplifier
In the present work, a highly sensitive sandwich-type electrochemical immunosensor of carcinoembryonic antigen (CEA) was developed by preparing N-doped hollow mesoporous nanocarbon spheres/gold hybrids (NHMN/A...
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Article
Open AccessInhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth
Targeting AKT suppresses tumor growth through inducing apoptosis, however, during which whether other forms of cell death occurring is poorly understood.
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Chapter and Conference Paper
Time-of-Use Scheduling Problem with Equal-Length Jobs
In this paper, we study the scheduling problem recently introduced by Wan and Qi [NRL’2010]. We are given a set of jobs to be scheduled on a single machine, in which the cost of scheduling a job depends on whe...
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Article
Open AccessTargeting ERK induced cell death and p53/ROS-dependent protective autophagy in colorectal cancer
In recent years, many studies have shown that autophagy plays a vital role in the resistance of tumor chemotherapy. However, the interaction between autophagy and cell death has not yet been clarified. In this...
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Article
Open AccessSNP rs12982687 affects binding capacity of lncRNA UCA1 with miR-873-5p: involvement in smoking-triggered colorectal cancer progression
This investigation was arranged to elucidate whether single nucleotide polymorphisms (SNPs) of lncRNA UCA1 was implicated in elevating colorectal cancer (CRC) risk by interacting with environmental exposures.
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Article
Transcriptome analysis reveals the effects of grafting on sweetpotato scions during the full blooming stages
Sweetpotato (Ipomoea batatas) is a hexaploid plant and generally most genotypes do not flower at all in sub-tropics. Heterografting was carried out between sweetpotato cultivar ‘Xushu 18’ and Japanese morning glo...
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Article
Open AccessThe wild sweetpotato (Ipomoea trifida) genome provides insights into storage root development
Sweetpotato (Ipomoea batatas (L.) Lam.) is the seventh most important crop in the world and is mainly cultivated for its underground storage root (SR). The genetic studies of this species have been hindered by a ...
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Article
Structural basis of outer membrane protein insertion by the BAM complex
All Gram-negative bacteria, mitochondria and chloroplasts have outer membrane proteins (OMPs) that perform many fundamental biological processes. The OMPs in Gram-negative bacteria are inserted and folded into...
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Article
De novo transcriptome assembly of Ipomoea nil using Illumina sequencing for gene discovery and SSR marker identification
Ipomoea nil is widely used as an ornamental plant due to its abundance of flower color, but the limited transcriptome and genomic data hinder research on it. Using illumina platform, tran...
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Article
Open AccessOptimal assembly strategies of transcriptome related to ploidies of eukaryotic organisms
Several de novo transcriptome assemblers have been developed recently to assemble the short reads generated from the next-generation sequencing platforms and different strategies were employed for assembling tran...
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Article
Structural basis for outer membrane lipopolysaccharide insertion
Lipopolysaccharide (LPS) is essential for most Gram-negative bacteria and has crucial roles in protection of the bacteria from harsh environments and toxic compounds, including antibiotics. Seven LPS transport...
