Cancer Chemotherapy and Selective Drug Development
Proceedings of the 10th Anniversary Meeting of the Coordinating Committee for Human Tumour Investigations, Brighton, England, October 24–28, 1983
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Open AccessA master protocol to investigate a novel therapy acetyl-l-leucine for three ultra-rare neurodegenerative diseases: Niemann-Pick type C, the GM2 gangliosidoses, and ataxia telangiectasia
The lack of approved treatments for the majority of rare diseases is reflective of the unique challenges of orphan drug development. Novel methodologies, including new functionally relevant endpoints, are need...
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Article
Results of the U-Pb age of detrital zircons from Upper Proterozoic deposits of the eastern slope of the Anabar uplift
The Upper Proterozoic sequence in the southern part of the East Anabar Basin, as throughout the entire framing of the Anabar uplift, has a two-unit terrigenous-carbonate structure. The results of the U-Pb dati...
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Article
Germline genetic variants in ABCB1, ABCC1 and ALDH1A1, and risk of hematological and gastrointestinal toxicities in a SWOG Phase III trial S0221 for breast cancer
Hematological and gastrointestinal toxicities are common among patients treated with cyclophosphamide and doxorubicin for breast cancer. To examine whether single-nucleotide polymorphisms (SNPs) in key pharmac...
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Article
Age and provenances of sandstones from the Riphean Priozersk and Salmi formations in the eastern Pasha-Ladoga basin (southern margin of the Baltic Shield)
The data on the age of sediments and their sources were first obtained by isotopic methods and lithological-petrographic observations for the Priozersk and Salmi formations in the northeastern Pasha-Ladoga bas...
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Article
Teaching Contemporary Physics Topics Using Real-Time Data Obtained via the World Wide Web
As a teaching tool, the World Wide Web (WWW) is unprecedented in its ability to transmit information and enhance communication between scientist and student. Just beginning to be developed are sites that activ...
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Tacrolimus: a new agent for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation
Tacrolimus (FK506) is a macrolide lactone with potent immunosuppressive activity 100 times that of cyclosporine by weight. The molecular mechanism of action is mediated via an inhibition of the phosphorylase a...
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Book
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Chapter and Conference Paper
A New Accelerator-Based Neutron Radiography System
A new neutron radiography system capable of accomodating an accelerator source of neutrons has been developed at IRT Corporation. The system was designed, constructed, and tested in response to the growing int...
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Book reviews
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Chapter and Conference Paper
Cytokinin Relations in the Whole Plant
Cytokinin levels in Xanthium strumarium decline rapidly throughout the plant after only one short-day cycle. This effect appears to be due to reduced cytokinin production by the roots, in response to a signal pro...
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Chapter and Conference Paper
The distance of symmetric spaces from ℓ p (n)
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Article
Noise measurements of gravitational-radiation antenna at liquid-nitrogen temperatures
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Chapter and Conference Paper
Time Delay Statistics of Photoelectric Emissions: An Experimental Test of Classical Radiation Theory
For many years the photoelectric effect has been taken to provide evidence for the quantum nature of electromagnetic radiation. However, as has been pointed out from time to time[1–3], if the electromagnetic f...
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Cancer Chemotherapy
Cancer Chemotherapy
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Article
Report on the chemotherapy section of the VIIth International Cancer Congress
Die Chemotherapie von bösartigen Gechwülsten und Leukämien wurde am VII. Internationalen Krebskongress in London sowohl vom Gesichtspunkt der Klinik wie von demjenigen der experimentellen Forschung aus behandelt.
