Cancer Chemotherapy and Selective Drug Development
Proceedings of the 10th Anniversary Meeting of the Coordinating Committee for Human Tumour Investigations, Brighton, England, October 24–28, 1983
Article
The lack of approved treatments for the majority of rare diseases is reflective of the unique challenges of orphan drug development. Novel methodologies, including new functionally relevant endpoints, are need...
Article
The Upper Proterozoic sequence in the southern part of the East Anabar Basin, as throughout the entire framing of the Anabar uplift, has a two-unit terrigenous-carbonate structure. The results of the U-Pb dati...
Article
Hematological and gastrointestinal toxicities are common among patients treated with cyclophosphamide and doxorubicin for breast cancer. To examine whether single-nucleotide polymorphisms (SNPs) in key pharmac...
Article
The data on the age of sediments and their sources were first obtained by isotopic methods and lithological-petrographic observations for the Priozersk and Salmi formations in the northeastern Pasha-Ladoga bas...
Article
As a teaching tool, the World Wide Web (WWW) is unprecedented in its ability to transmit information and enhance communication between scientist and student. Just beginning to be developed are sites that activ...
Article
Tacrolimus (FK506) is a macrolide lactone with potent immunosuppressive activity 100 times that of cyclosporine by weight. The molecular mechanism of action is mediated via an inhibition of the phosphorylase a...
Book
Proceedings of the 10th Anniversary Meeting of the Coordinating Committee for Human Tumour Investigations, Brighton, England, October 24–28, 1983
Chapter and Conference Paper
A new neutron radiography system capable of accomodating an accelerator source of neutrons has been developed at IRT Corporation. The system was designed, constructed, and tested in response to the growing int...
Article
Chapter and Conference Paper
Cytokinin levels in Xanthium strumarium decline rapidly throughout the plant after only one short-day cycle. This effect appears to be due to reduced cytokinin production by the roots, in response to a signal pro...
Chapter and Conference Paper
Article
Chapter and Conference Paper
For many years the photoelectric effect has been taken to provide evidence for the quantum nature of electromagnetic radiation. However, as has been pointed out from time to time[1–3], if the electromagnetic f...
Article
Cancer Chemotherapy
Article
Die Chemotherapie von bösartigen Gechwülsten und Leukämien wurde am VII. Internationalen Krebskongress in London sowohl vom Gesichtspunkt der Klinik wie von demjenigen der experimentellen Forschung aus behandelt.