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Article
Noncanonical open reading frames encode functional proteins essential for cancer cell survival
Although genomic analyses predict many noncanonical open reading frames (ORFs) in the human genome, it is unclear whether they encode biologically active proteins. Here we experimentally interrogated 553 candi...
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Article
Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase
A transgenic mouse strain with early and uniform expres sion of the Cre site-specific recombinase is described. In this strain, PGK-Crem, Cre is driven by the early acting PGK-1 promoter, but, probably due to ...