21 Result(s)
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Article
Open AccessPartial dechlorination of 2,4,4′-trichlorobiphenyl (PCB 28) mediated by recombinant human CYP1A2
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Article
Open AccessTen years after: findings from the medical surveillance program on Health Effects in High-Level Exposure to PCB (HELPcB)
After the detection of high environmental and occupational exposure to polychlorinated biphenyls (PCBs) in a German recycling company for transformers and capacitors in 2010, the multidisciplinary medical surv...
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Article
Open AccessThe human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro
Short-term inhalation of occupationally relevant ultrafine zinc/copper (Zn/Cu) containing welding fumes has been shown to induce subclinical systemic inflammation, associated with an elevated risk for cardiova...
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Article
Open AccessThe pupillary light reflex (PLR) as a marker for the ability to work or drive – a feasibility study
The PLR (pupillary light reflex) can be a marker for pathological medical conditions, such as neurodegenerative or mental health disorders and diseases as well as marker for physiological alterations, such as ...
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Article
Open AccessLongitudinal changes in telomere length in PCB-exposed individuals: interaction with CMV infection
We recently demonstrated a significant shortening of age-adapted telomere length (TL) in lymphocytes of polychlorinated biphenyls (PCB)-exposed individuals. Here, we analyzed TL in individuals of the same PCB-...
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Reference Work Entry In depth
Medical Aspects of Traffic Exhaust Regulations
Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...
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Living Reference Work Entry In depth
Medical Aspects of Traffic Exhaust Regulations
Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...
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Article
Dirty deeds done dirt cheap: sensitization of prostate cancer cells to abiraterone treatment using hydroxylated polychlorinated biphenyls
Effective targeting of androgen biosynthesis by the 17α-hydroxylase/17,20-lyase inhibitor abiraterone prolongs survival in a variety of prostate cancer patients. However, resistance to abiraterone treatment oc...
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Article
Open AccessDoes stigmatization moderate the association between intention and implementation of learned prevention-strategies at work after a depressive episode? – a cross-sectional pilot study
A depressive episode is a frequent reason for production loss due to long periods of absence at work. To maintain work ability after depression, affected employees need to implement learned co** strategies f...
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Article
Open AccessAssociation of plasma PCB levels and HbA1c concentration in Iran
The rapid increase in prevalence of diabetes mellitus over the last decades warrants more attention to the effects of environmental and occupational exposures on glucose metabolism. Our study aimed to assess t...
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Article
Open AccessMigrating pleural plaque in a patient with asbestos induced pleural disease: a case report
Health surveillance of formerly asbestos exposed individuals focus on early detection of asbestos related diseases, such as lung fibrosis (asbestosis), pleural plaques, mesothelioma and lung cancer in particul...
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Article
Open AccessAccelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure
Polychlorinated biphenyls (PCBs) are organochlorine pollutants with a worldwide dissemination. We examined telomere length (TL) in peripheral blood cells of 207 individuals with a high body burden of PCBs due ...
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Article
Open AccessA technical support tool for joint range of motion determination in functional diagnostics - an inter-rater study
The examination of joint range of motion (RoM) is part of musculo-skeletal functional diagnostics, used, for example, in occupational examinations. Various examination methodologies exist that have been optimi...
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Article
Open AccessRadiological surveillance of formerly asbestos-exposed power industry workers: rates and risk factors of benign changes on chest X-ray and MDCT
To determine the prevalence of asbestos-related changes on chest X-ray (CXR) and low-dose multidetector-row CT (MDCT) of the thorax in a cohort of formerly asbestos-exposed power industry workers and to assess...
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Article
Open AccessIs it useful to combine sputum cytology and low-dose spiral computed tomography for early detection of lung cancer in formerly asbestos-exposed power industry workers?
Low-dose spiral computed tomography (LDSCT) in comparison to conventional chest X-ray proved to be a highly sensitive method of diagnosing early stage lung cancer. However, centrally located early stage lung t...
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Article
Open AccessRetrospective exposure assessment to airborne asbestos among power industry workers
A method of individually assessing former exposure to asbestos fibres is a precondition of risk-differentiated health surveillance. The main aims of our study were to assess former levels of airborne asbestos ...
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Article
Memantine Pharmacotherapy
Memantine plasma concentrations show considerable interindividual variability. High memantine plasma concentrations are associated with the occurrence of neuropsychiatric adverse effects such as confusion. The...
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Article
Open AccessAnalysing the causes of chronic cough: relation to diesel exhaust, ozone, nitrogen oxides, sulphur oxides and other environmental factors
Air pollution remains a leading cause of many respiratory diseases including chronic cough. Although episodes of incidental, dramatic air pollution are relatively rare, current levels of exposure of pollutants...
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Article
Open AccessMethod optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry
Determinations of inflammatory markers in exhaled breath condensate were used to assess airway inflammation. The most applied method for this kind of determination is enzyme immunoassay. For research purposes ...
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Article
Open AccessAluminosis – Detection of an almost forgotten disease with HRCT
The aim of this study was to investigate whether it is possible to detect high-resolution computed tomography (HRCT) findings in aluminium powder workers, which are consistent with early stages of aluminosis.
