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  1. Article

    Open Access

    Partial dechlorination of 2,4,4′-trichlorobiphenyl (PCB 28) mediated by recombinant human CYP1A2

    Isabella Randerath, Natalia Quinete, Julian Peter Müller in Archives of Toxicology (2024)

  2. Article

    Open Access

    Ten years after: findings from the medical surveillance program on Health Effects in High-Level Exposure to PCB (HELPcB)

    After the detection of high environmental and occupational exposure to polychlorinated biphenyls (PCBs) in a German recycling company for transformers and capacitors in 2010, the multidisciplinary medical surv...

    Jens Rengelshausen, Isabella Randerath, Thomas Schettgen in Archives of Toxicology (2023)

  3. Article

    Open Access

    The human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro

    Short-term inhalation of occupationally relevant ultrafine zinc/copper (Zn/Cu) containing welding fumes has been shown to induce subclinical systemic inflammation, associated with an elevated risk for cardiova...

    Theresa Scheurer, Jan Steffens in Journal of Occupational Medicine and Toxic… (2022)

  4. Article

    Open Access

    The pupillary light reflex (PLR) as a marker for the ability to work or drive – a feasibility study

    The PLR (pupillary light reflex) can be a marker for pathological medical conditions, such as neurodegenerative or mental health disorders and diseases as well as marker for physiological alterations, such as ...

    Andrea Kaifie, Martin Reugels, Thomas Kraus in Journal of Occupational Medicine and Toxic… (2021)

  5. Article

    Open Access

    Human detection thresholds of DC, AC, and hybrid electric fields: a double-blind study

    In the course of the ongoing transition of electric energy systems, transmission corridors are often upgraded to higher voltages and other technologies leading to another quality of human exposure. The study a...

    Michael Kursawe, Dominik Stunder, Thomas Krampert, Andrea Kaifie in Environmental Health (2021)

  6. Article

    Open Access

    Longitudinal changes in telomere length in PCB-exposed individuals: interaction with CMV infection

    We recently demonstrated a significant shortening of age-adapted telomere length (TL) in lymphocytes of polychlorinated biphenyls (PCB)-exposed individuals. Here, we analyzed TL in individuals of the same PCB-...

    Fabian Beier, Andre Esser, Lucia Vankann, Anne Abels in Archives of Toxicology (2021)

  7. No Access

    Reference Work Entry In depth

    Medical Aspects of Traffic Exhaust Regulations

    Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...

    Andrea Kaifie, Thomas Kraus in Regulatory Toxicology (2021)

  8. No Access

    Living Reference Work Entry In depth

    Medical Aspects of Traffic Exhaust Regulations

    Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...

    Andrea Kaifie, Thomas Kraus in Regulatory Toxicology

  9. Article

    Open Access

    Does stigmatization moderate the association between intention and implementation of learned prevention-strategies at work after a depressive episode? – a cross-sectional pilot study

    A depressive episode is a frequent reason for production loss due to long periods of absence at work. To maintain work ability after depression, affected employees need to implement learned co** strategies f...

    Petra Maria Gaum, Franziska Brey in Journal of Occupational Medicine and Toxic… (2019)

  10. Article

    Open Access

    Association of plasma PCB levels and HbA1c concentration in Iran

    The rapid increase in prevalence of diabetes mellitus over the last decades warrants more attention to the effects of environmental and occupational exposures on glucose metabolism. Our study aimed to assess t...

    Sahar Eftekhari, Omid Aminian in Journal of Occupational Medicine and Toxic… (2018)

  11. Article

    Open Access

    Polychlorinated biphenyls and depression: cross-sectional and longitudinal investigation of a dopamine-related Neurochemical path in the German HELPcB surveillance program

    Exposure to polychlorinated biphenyls (PCBs) is associated with depressive symptomatology. A cause of depressive symptoms is a disturbance in the neurotransmitter system of dopamine (DA). Animal as well as hum...

    Petra Maria Gaum, Monika Gube, Thomas Schettgen in Environmental Health (2017)

  12. Article

    Open Access

    Migrating pleural plaque in a patient with asbestos induced pleural disease: a case report

    Health surveillance of formerly asbestos exposed individuals focus on early detection of asbestos related diseases, such as lung fibrosis (asbestosis), pleural plaques, mesothelioma and lung cancer in particul...

    Christian Eisenhawer, Michael K. Felten in Journal of Occupational Medicine and Toxic… (2017)

  13. Article

    Open Access

    Biological effects of exposure to static electric fields in humans and vertebrates: a systematic review

    High-voltage direct current (HVDC) lines are the technology of choice for the transport of large amounts of energy over long distances. The operation of these lines produces static electric fields (EF), but th...

    Anne-Kathrin Petri, Kristina Schmiedchen, Dominik Stunder in Environmental Health (2017)

  14. Article

    Open Access

    Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure

    Polychlorinated biphenyls (PCBs) are organochlorine pollutants with a worldwide dissemination. We examined telomere length (TL) in peripheral blood cells of 207 individuals with a high body burden of PCBs due ...

    Susanne Ziegler, Thomas Schettgen, Fabian Beier, Stefan Wilop in Archives of Toxicology (2017)

  15. No Access

    Article

    Human biomonitoring of aluminium after a single, controlled manual metal arc inert gas welding process of an aluminium-containing worksheet in nonwelders

    Several existing field studies evaluate aluminium welding works but no thoroughly controlled exposure scenario for welding fume has been described yet. This study provides information about the uptake and elim...

    Jens Bertram, Peter Brand, Laura Hartmann in International Archives of Occupational and… (2015)

  16. Article

    Open Access

    A technical support tool for joint range of motion determination in functional diagnostics - an inter-rater study

    The examination of joint range of motion (RoM) is part of musculo-skeletal functional diagnostics, used, for example, in occupational examinations. Various examination methodologies exist that have been optimi...

    Christoph Schiefer, Thomas Kraus in Journal of Occupational Medicine and Toxic… (2015)

  17. Article

    Open Access

    Radiological surveillance of formerly asbestos-exposed power industry workers: rates and risk factors of benign changes on chest X-ray and MDCT

    To determine the prevalence of asbestos-related changes on chest X-ray (CXR) and low-dose multidetector-row CT (MDCT) of the thorax in a cohort of formerly asbestos-exposed power industry workers and to assess...

    Christian Eisenhawer, Michael K Felten in Journal of Occupational Medicine and Toxic… (2014)

  18. Article

    Open Access

    Is it useful to combine sputum cytology and low-dose spiral computed tomography for early detection of lung cancer in formerly asbestos-exposed power industry workers?

    Low-dose spiral computed tomography (LDSCT) in comparison to conventional chest X-ray proved to be a highly sensitive method of diagnosing early stage lung cancer. However, centrally located early stage lung t...

    Michael K Felten, Lars Knoll in Journal of Occupational Medicine and Toxic… (2014)

  19. No Access

    Article

    Changes of mesothelin and osteopontin levels over time in formerly asbestos-exposed power industry workers

    In patients develo** malignant pleural mesothelioma (MPM) or lung cancer, using effective tumour markers is the quickest way to ensure early diagnosis and improve survival time. The aim of our study was to a...

    Michael K. Felten, Khaled Khatab, Lars Knoll in International Archives of Occupational and… (2014)

  20. No Access

    Article

    The incremental effect of psychosocial workplace factors on the development of neck and shoulder disorders: a systematic review of longitudinal studies

    To systematically analyse evidence on the incremental effect of work-related psychosocial risk factors on the development of neck and shoulder disorders, as reported in longitudinal studies.

    Silvia Kraatz, Jessica Lang, Thomas Kraus in International Archives of Occupational and… (2013)

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