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Article
Open AccessHighly variable friction and slip observed at Antarctic ice stream bed
The slip of glaciers over the underlying bed is the dominant mechanism governing the migration of ice from land into the oceans, with accelerating slip contributing to sea-level rise. Yet glacier slip remains ...
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Article
Open AccessDum** behaviour of Australian desert ants (Melophorus bagoti) (Hymenoptera:Formicidae)
The Central Australian desert ant Melophorus bagoti maintains ground-nesting colonies in the semi-desert habitat. These ants manage waste by dum** items outside the nest. To examine this process, we placed orga...
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Article
Investigation of the Effects of Forming Gas Annealing on Al2O3/GaN Interface
In this work, the effects of post-deposition annealing in forming gas ambient on the structure of the Al2O3/GaN interface are investigated. Using capacitance–voltage (C–V) and conductance–frequency (G–f) measurem...
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Article
Quality of life in patients undergoing repetitive TACE for the treatment of intermediate stage HCC
With a limited overall survival (OS) of 20 months in patients diagnosed with intermediate stage hepatocellular carcinoma (HCC), the preservation of quality of life (QoL) during transarterial chemoembolization ...
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Article
Open AccessGlyco-engineered anti-EGFR mAb elicits ADCC by NK cells from colorectal cancer patients irrespective of chemotherapy
The epidermal growth factor receptor (EGFR) is overexpressed in colorectal cancer (CRC), and is correlated with poor prognosis, making it an attractive target for monoclonal antibody (mAb) therapy. A component...
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Article
Qualitative veterinary risk assessment of the role of wild deer in the likelihood of incursion and the impact on effective disease control of selected exotic notifiable diseases in England
A qualitative risk assessment was undertaken to analyse the likelihood of the incursion of selected exotic infectious disease into deer populations in GB and the potential impacts these animals could have on e...
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Article
Approach to biliary imaging amongst consultant and specialist registrars in gastroenterology in a national setting
Radiological investigation plays an important role in the management of conditions affecting the hepatobiliary system. However, multiple imaging modalities exist and inappropriate requesting can lead to delays...
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Article
Rationale, design and methods of the HEALTHY study physical education intervention component
The HEALTHY primary prevention trial was designed to reduce risk factors for type 2 diabetes in middle school students. Middle schools at seven centers across the United States participated in the 3-year study...
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Article
Growth and Characterization of Carbon Nanopearls on a Si Substrate by CVD Process
Carbon nanopearls have been found to form on a Si substrate when grown at 850°C, using the chemical vapor deposition process (CVD). An acetylene carbon source and a Ni catalyst are the main ingredients for thi...
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Chapter and Conference Paper
Ultra High-Resolution Optical Coherence Tomography for Ocular Imaging of Small Animals
Accurate in-vivo evaluation of the structural and morphological changes of the ocular structures of small animal models is essential in understanding the disease mechanisms, monitoring the disease progression,...
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Article
Rare cerebellar metastases from oesophageal carcinoma
Metastatic oesophageal carcinoma to the brain is an uncommon diagnosis that may cause abnormal neurological findings.
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Article
Effect of raloxifene and its interaction with human PTH on bone formation
We studied the of effects raloxifene alone or in combination with human PTH (hPTH) 1–34 in mineralizing cultures of SaOS-2 cells. Raloxifene (10−8–10−6 M) increased bone nodule formation in cultures of SaOS-2 cel...
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Article
Open AccessRapid access multidisciplinary lymph node diagnostic clinic: analysis of 550 patients
Lymphadenopathy is common, affecting patients of all ages. The current referral pattern for investigating patients with lymphadenopathy varies widely with no universally practised pathway. Our institution set ...
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Article
The Influence of Osteoporotic Fractures on Health-Related Quality of Life in Community-Dwelling Men and Women across Canada
Health-related quality of life (HRQL) was examined in relation to prevalent fractures in 4816 community-dwelling Canadian men and women 50 years and older participating in the Canadian Multicentre Osteoporosi...
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Article
Spectral-Component Monitoring of the Plumes Generated during the Deposition of RE(Y, Nd) Ba2Cu3O7−x Films by Pulsed Laser Ablation
Yba2Cu3OT7−x (Y123) and NdBa2Cu3O7−x (Nd123) thin films were deposited by PLD using a 248 nm wavelength KrF excimer laser. The emission spectra PLD process control techniques developed to grow reproducibly high q...
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Article
The distribution of alternative agents for targeted radiotherapy within human neuroblastoma spheroids
This study aims to select the radiopharmaceutical vehicle for targeted radiotherapy of neuroblastoma which is most likely to penetrate readily the centre of micrometastases in vivo. The human neuroblastoma cel...
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Article
The use of angiotensin II as a potential method of targeting cytotoxic microspheres in patients with intrahepatic tumour
Cytotoxic microspheres have been developed for intra-arterial use in patients with liver metastases. Following injection, the distribution of microspheres reflects the pattern of hepatic arterial blood-flow. V...
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Article
A comparative study of the relative sensitivity and specificity of radiolabelled monoclonal antibody and computerised tomography in the detection of sites of disease in human malignant melanoma
A monoclonal antibody raised against the high molecular weight melanoma antigen was labelled with indium-111 and injected intravenously into 25 patients with malignant melanoma. The results obtained from image...
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Article
A tumour spheroid model for antibody-targeted therapy of micrometastases
Human neuroblastoma cells grown as tumour spheroids were briefly incubated with a conjugate of 131I and an anti-human neuroectodermal monoclonal antibody UJ13A. Unbound 131I was removed by washing and the sphe...
