-
Article
Open AccessThe Glioma-IRE project − Molecular profiling in patients with glioma: steps toward an individualized diagnostic and therapeutic approach
This study aimed to characterize the genetic profile of patients with glioma and discuss the impact of next-generation sequencing in glioma diagnosis and treatment.
-
Article
Recurrent glioblastoma: which treatment? A real-world study from the Neuro-oncology Unit “Regina Elena” National Cancer Institute
The majority of patients with glioblastoma (GBM) experience disease progression. At recurrence, treatment options have limited efficacy. Many studies report a limited and short duration response rate. Although...
-
Article
Open AccessA PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions
-
Article
Surgical treatment of intramedullary spinal cord metastases: functional outcome and complications—a multicenter study
Intramedullary spinal cord metastasis (ISCM) is a rare event in the course of advanced malignancy. Management of these lesions remains controversial. Recently, surgery for ISCM has been advocated for selected ...
-
Article
Surgical treatment of solitary intradural extramedullary spinal cord metastases from solid cancers of non-neurogenic origin. A multicenter study
Intradural extramedullary spinal metastases (IESM) represent an extremely rare manifestation of systemic cancer. We evaluated the surgical indications, complications and outcome in a series of 43 patients with...
-
Chapter
Correction to: Pathologic Vertebral Fractures
The below details were missing in Table 11.1 and the same has been updated in this erratum.
-
Chapter
Technique of Kyphoplasty
Balloon kyphoplasty (BKP) differs from vertebroplasty since an inflatable bone tamps or balloon, is inserted into the vertebral body, before the injection of the filling material, with the aim to elevate the e...
-
Chapter
Traumatic Vertebral Fractures
Traumatic vertebral fractures are the result of high-energy blunt trauma and account for 6% of all fractures. Sixty-five percent of these fractures occur due to motor vehicle accidents and falls from height an...
-
Chapter
Biomechanics of the Spine and Materials Employed in Vertebroplasty, Kyphoplasty, and Augmentation Techniques
The aim of this chapter is to describe the changes in spine biomechanics of patients with osteoporotic Vertebral Compression Fractures (VCFs) and to investigate the main features of filler materials employed f...
-
Chapter
Technique of Vertebroplasty
Vertebroplasty (VP) involves the injection of a filling material into an injured vertebral body via a working cannula, usually placed through a transpedicular or extra-pedicular approach. In this chapter a ste...
-
Chapter
Future Developments of Vertebroplasty and Kyphoplasty Techniques
Augmented Reality (AR) with Artificial Intelligence (AI) is a novel navigational technique that superimposes virtual 3D anatomic data onto real-world 2D visual images in real time. 3D volumetric data are acqui...
-
Chapter
Alternative Techniques: Elastoplasty, Vesselplasty, The Kiva System, Spine Jack, Lordoplasty, and Discoplasty
Although vertebroplasty (VP) and balloon kyphoplasty (BKP) are highly common procedures in the management of vertebral fractures, their use over the years has raised a number of questions that promoted the dev...
-
Chapter
Surgical and Radiological Anatomy of the ThoracoLumbar Spine for Vertebroplasty and Kyphoplasty
The vertebral column is a complex anatomical structure which ensures the protection of the spinal cord and the stability of the body. Although limited motions are available between adjacent vertebrae, taken to...
-
Chapter
Pathologic Vertebral Fractures
Skeleton metastases are detected in approximately 30–70% of cancer patients during their clinical course and the spinal column is involved in up to 50% of such cases. Metastatic spine disease represents more t...
-
Chapter
Indications and Contraindication of Vertebroplasty and Kyphoplasty
The aims of augmentation procedures as vertebroplasty (VP) and balloon kyphoplasty (BKP) are to strengthen the vertebral body and to improve mechanical pain induced by different pathologic conditions. The indi...
-
Chapter
Innovative Brachytherapy Techniques and Radiofrequency Ablation
Brachytherapy is a type of radiation therapy that utilizes natural or manufactured radioactive isotopes or radionuclides implanted in the internal organs of the body, to treat cancer lesions, with the aim to d...
-
Chapter
Complication Avoidance and Management
Even if standard vertebroplasty (VP) and balloon kyphoplasty (BKP) are perceived as percutaneous mini-invasive surgical techniques and serious consequences are rare, compared to the number of procedures annual...
-
Chapter
Vertebroplasty and Kyphoplasty: An Overview
Vertebroplasty and Kyphoplasty are mini-invasive surgical procedures that, since their introduction about 30 years ago, have gained an increased popularity for the treatment of symptomatic vertebral compressio...
-
Chapter
Open Kyphoplasty and its Role in “Separation Surgery”
Different surgical options are available for the heterogeneous clinical conditions related to neoplastic spinal disorders and must be individualized to the specific needs of the single patient. Whenever excisi...
-
Chapter
Osteoporotic Vertebral Fractures
Osteoporosis is the most common metabolic disorder of the bone, affecting approximately 100 million people worldwide. Even if it is considered a women’s health issue, osteoporosis affects also 33% of men by th...
