SpringerLink
Log in

Vertebroplasty and Kyphoplasty: An Overview

  • Chapter
  • First Online:
Vertebral Body Augmentation, Vertebroplasty and Kyphoplasty in Spine Surgery

  • 723 Accesses

Abstract

Vertebroplasty and Kyphoplasty are mini-invasive surgical procedures that, since their introduction about 30 years ago, have gained an increased popularity for the treatment of symptomatic vertebral compression fractures. Due to the reported positive results in terms of increased pain control, quality of life, and spinal stability, the surgical indications have progressively expanded encompassing vertebral angiomas, osteoporotic, traumatic and pathologic vertebral lesions. In this chapter, the history and development of such techniques have been briefly reviewed, as well as the main results, guidelines, controversial topics, and recent developments that emerged from the literature.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
EUR 29.95
Price includes VAT (France)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
EUR 93.08
Price includes VAT (France)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
EUR 116.04
Price includes VAT (France)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info
Hardcover Book
EUR 158.24
Price includes VAT (France)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Anselmetti GC, Manca A, Tutton S, Chiara G, Kelekis A, Facchini FR, Russo F, Regge D, Montemurro F. Percutaneous vertebral augmentation assisted by PEEK implant in painful osteolytic vertebral metastasis involving the vertebral wall: experience on 40 patients. Pain Physician. 2013;16(4):E397–404.

    Article  PubMed  Google Scholar 

  • Armsen N, Boszczyk B. Vertebro/Kyphoplasty history, development, results. Eur J Trauma. 2005;5:433–40.

    Article  Google Scholar 

  • Buchbinder R, Osborne RH, Ebeling PR, et al. A randomized controlled trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med. 2009;361:557–68.

    Article  CAS  Google Scholar 

  • Burton AW, Mendoza T, Gebhardt R, Hamid B, Nouri K, Perez-Toro M, et al. Vertebral compression fracture treatment with vertebroplasty and kyphoplasty: experience in 407 patients with 1156 fracture in a tertiary cancer center. Pain Med. 2011;12:1750–7.

    Article  PubMed  Google Scholar 

  • Chen AT, Cohen DB, Skolasky RL. Impact of nonoperative treatment, vertebroplasty, and kyphoplasty on survival and morbidity after vertebral compression fracture in the medicare population. J Bone Joint Surg Am. 2013;95:1729–36.

    Article  PubMed  Google Scholar 

  • Cooper C, Atkinson EJ, O’Fallon WM, et al. Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota, 1985–1989. J Bone Miner Res. 1992;7:221–7.

    Article  CAS  PubMed  Google Scholar 

  • Denaro V, Longo UM, Maffulli N, Denaro L. Vertebroplasty and kyphoplasty. Clin Cases Miner Bone Metab. 2009;6(2):125–30.

    PubMed  Google Scholar 

  • Deramond H, Depriester C, Galibert P, et al. Percutaneous vertebroplasty with polymethylmethacrylate: technique, indications, and results. Radiol Clin North Am. 1998;36:533–46.

    Article  CAS  PubMed  Google Scholar 

  • Diel P, Röder C, Perler G, Vordemvenne T, Scholz M, Kandziora F, Fürderer S, Eiskjaer S, Maestretti G, Rotter R, Benneker LM, Heini PF. Radiographic and safety details of vertebral body stenting: results from a multicenter chart review. BMC Musculoskelet Disord. 2013;14:233.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ebeling PR, Akesson K, Bauer DC, et al. The efficacy and safety of vertebral augmentation: a second ASBMR task force report. JBMR. 2019;34:3–21.

    Article  Google Scholar 

  • Eichholz KM, O’Toole J, Christie SD, Fessler RG. Vertebroplasty and kyphoplasty. Neurosurg Clin N Am. 2006;17:507–18.

    Article  PubMed  Google Scholar 

  • El Fiki M. Vertebroplasty, kyphoplasty, lordoplasty, expandable devices and current treatment of painful osteoporotic vertebral fractures. World Neurosurg. 2016;91:628–32.

    Article  PubMed  Google Scholar 

  • Epstein N. A comparison of kyphoplasty, vertebroplasty, or non-surgical treatment of traumatic/atraumatic osteoporotic vertebral compression fractures: a short review. Surg Neurol Int. 2019;10(54):3–5.

    Google Scholar 

  • Galibert P, Deramond H, Rosat P. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie. 1987;33:166–8.

    CAS  PubMed  Google Scholar 

  • Gangi A, Kastler BA, Dietemann JL. Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. AJNR Am J Neuroradiol. 1994;15:83–6.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Garfin S, Lin G, Lieberman I, et al. Retrospective analysis of the outcomes of balloon kyphoplasty to treat vertebral body compression fracture (VCF) refractory to medical management. Eur Spine J. 2001a;10(Suppl):S7.

    Google Scholar 

  • Garfin SR, Yuan HA, Reiley MA. New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine. 2001b;26:1511–5.

    Article  CAS  PubMed  Google Scholar 

  • Gu CN, Brinjiikji W, Evans AJ, Murad MH, Kallmes DF. Outcomes of vertebroplasty compared with kyphoplasty: a systematic review and meta-analysis. J Neurointerv Surg. 2016;8(6):636–42.

    Article  PubMed  Google Scholar 

  • Harrington KD. The use of methylmethacrylate for vertebral-body replacement and anterior stabilization of pathological fracture-dislocations of the spine due to metastatic malignant disease. J Bone Joint Surg Am. 1981;63(1):36–46.

    Article  CAS  PubMed  Google Scholar 

  • He Z, Zhai Q, Hu M, Cao C, Wang J, Yang H, Li B. Bone cements for percurtaneous vertebroplasty and balloon khyphoplasty: current status and future development. J Orthopaed Transl. 2015;3:1–11.

    Article  CAS  Google Scholar 

  • Health Quality Ontario. Vertebral health technology involving vertebroplasty or kyphoplasty for cancer-related vertebral compression fractures: a systematic review. J Neurointerv Surg. 2016;16(1).

    Google Scholar 

  • Heini PF, Orler R. Vertebroplasty in severe osteoporosis. Technique and experience with multi-segment injection. Orthopade. 2004;33(1):22–30.

    Article  CAS  PubMed  Google Scholar 

  • Hsiang J. An unconventional indication for open kyphoplasty. Spine J. 2003;3:520–3.

    Article  PubMed  Google Scholar 

  • Hulme PA, Krebs J, Ferguson SJ, Berlemann U. Vertebroplasty and Kyphoplasty: a systematic review of 69 clinical studies. Spine. 2006;31(17):1983–2001.

    Article  PubMed  Google Scholar 

  • Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. AJNR Am J Neuroradiol. 1997;18:1897–904.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Jensen ME, McGraw JK, Cardella JF, et al. Position statement on percutaneous vertebral augmentation: a consensus statement developed by the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, American Association of Neurological Surgeons, Congress of Neurological Surgeons, and American Society of Spine Radiology. Am J Neuroradiol. 2007;28:1439–43.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Kaemmerlen P, Thiesse P, Bouvard H, Biron P, Momex F, Jonas P. Percutaneous vertebrolasty in the treatment of metastases. Technic and results. J Radiol. 1989;70:557–62.

    CAS  PubMed  Google Scholar 

  • Kallmes DF, Comstock BA, Heagerty PJ, et al. A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med. 2009;361:569–79.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Knavel EM, Thielen KR, Kallmes DF. Vertebroplasty for the treatment of traumatic nonosteoporotic compression fractures. Am J Neuroradiol. 2009;30(2):323–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Korovessis P, Vardakastanis K, Vitsas V, et al. Is Kiva implant advantageous to balloon kyphoplasty in treating osteolytic metastasis to the spine? Comparison of 2 percutaneous minimal invasive spine techniques: a prospective randomized controlled short-term study. Spine. 2014;39:E231–9.

    Article  PubMed  Google Scholar 

  • Lavelle W, Carl A, Lavelle ED, Khaleel MA. Vertebropalsty and kyphoplasty. Anesthesiol Clin. 2007;25(4):913–28.

    Article  PubMed  Google Scholar 

  • Ledlie JT, Renfro M. Balloon kyphoplasty: one-year outcomes in vertebral body height restoration, chronic pain, and activity levels. J Neurosurg. 2003;98(1 Suppl):36–42.

    PubMed  Google Scholar 

  • Lee MJ, Dumonsky M, Cahill P, Stanley T, Park D, Singh K. Percutaneous treatment of vertebral compression fractures: a meta-analysis of complications. Spine. 2009;34(11):1228–32.

    Article  PubMed  Google Scholar 

  • Lewis G. Alternatives to balloon Kyphoplasty for surgical treatment of vertebral compression fractures: a state-of-the-art review. J Adv Med Med Res. 2018;26(12):1–19.

    Article  Google Scholar 

  • Li HM, Zhang RJ, Gao H, Jia CY, Zhang JX, Dong FL, Shen CL. New vertebral fractures after osteoporotic vertebral compression fracture between balloon kyphoplasty and nonsurgical treatment. PRISMA. 2018;97:40.

    Google Scholar 

  • Lieberman IH, Dudeney S, Reinhardt MK, Bell G. Initial outcome and efficacy of “kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine. 2001;26:1631–8.

    Article  CAS  PubMed  Google Scholar 

  • Ma XL, **ng D, Ma JX, et al. Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis. Eur Spine J. 2012;21(9):1844–59.

    Article  PubMed  PubMed Central  Google Scholar 

  • Mathis JM, Barr JD, Belkoff SM, et al. Percutaneous vertebroplasty: a develo** standard of care for vertebral compression fractures. Am J Neuroradiol. 2001;22:373–38.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Munk PL, Rashid F, Heran MK, Papirny M, Liu DM, Malfair D, Badii M, Clarkson PW. Combined cementoplasty and radiofrequency ablation in the treatment of painful neoplastic lesions of bone. J Vasc Interv Radiol. 2009;20(7):903–11.

    Article  PubMed  Google Scholar 

  • Noriega D, Rodriguez Monsalve F, Ramajo R, Sanchez-Lite I, Toribio B, Ardura F. Long-term safety and clinical performance of kyphoplasty and SpineJack® procedures in the treatment of osteoporotic vertebral compression fractures: a pilot, monocentric, investigator-initiated study. Osteoporos Int. 2019;30(3):637–45.

    Article  CAS  PubMed  Google Scholar 

  • Ofluoglu O. Minimally invasive management of spinal metastases. Orthop Clin N Am. 2009;40:155–68.

    Article  Google Scholar 

  • Peh WC, Munk PL, Rashid F, Gilula LA. Percutaneous vertebral augmentation: vertebroplasty, kyphoplasty and skyphoplasty. Radiol Clin North Am. 2008;46:611–35.

    Article  PubMed  Google Scholar 

  • Ruiz Santiago F, Chinchilla AS, Alvarez LG, Abela ALP, Castellano Garcia MDM, Lopez MP. Comparative review of vertebroplasty and kyphoplasty. World J Radiol. 2014;6:329–43.

    Article  PubMed  PubMed Central  Google Scholar 

  • Sadeghi-Naini M, Aarabi A, Shokranesh F, Janani L, Vaccaro AR, Rahimi-Movaghar V. Vertebroplasty and kyphoplasty for metastatic spinal lesions. Clin Spine Surg. 2018;31(5):203–10.

    Article  PubMed  Google Scholar 

  • Schroeder JE, Ecker E, Skelly AC, Kaplan L. Cement augmentation in spinal tumors a systematic review comparing vertebroplasty and kyphoplasty. Evid Based Spine Care J. 2011;2(4):33–43.

    Google Scholar 

  • Sorensen ST, Kirkegaard AO, Carreon L, Rousing R, Andersen MO. Vertebroplasty or kyphoplasty as palliative treatment for cancer-related vertebral compression fractures: a systematic review. Spine J. 2019;19(6):1067–75.

    Article  PubMed  Google Scholar 

  • Stevenson M, Gomersall T, Lloyd JM, Rawdin A, Hernandez M, Dias S, Wilson D, Rees A. Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for the treatment of osteoporotic vertebral fractures: a systematic review and cost-effectiveness analysis. Health Technol Assess (Winch Eng). 2014;18(17):1–290.

    Google Scholar 

  • Taylor R, Fritzell P, Taylor RJ. Balloon kyphoplasty in the management of vertebral compression fractures: an update systematic review and meta-analyses. Eur Spine J. 2007;16(8):1085–100.

    Article  PubMed  PubMed Central  Google Scholar 

  • Telera S, Gorgoglione N, Raus L, Vidiri A, Villani V, Pace A, Fabi A, Crispo F, Castiglione M, Sperduti I, Boccaletti R. World Neurosurg. 2019;127:751–60.

    Article  Google Scholar 

  • Tsoumakidou G, Too CW, Koch G, Caudrelier J, Cazzato RL, Garnon J, Gangi A. CIRSE guidelines on percutaneous vertebral augmentation. Cardiovasc Intervent Radiol. 2017;40:331–42.

    Article  PubMed  Google Scholar 

  • Vogl TJ, Pflugmacher R, Hierholzer J, et al. Cement directed kyphoplasty reduces cement leakage as compared with vertebroplasty: results of a controlled, randomized trial. Spine. 2013;38(20):1730–6.

    Article  PubMed  Google Scholar 

  • Wang B, Zhao CP, Song LX, et al. Balloon kyphoplasty versus percutaneous vertebroplasty for osteoporotic vertebral compression fracture: a meta-analysis and systematic review. J Orthop Surg Res. 2018;13(1):264.

    Article  PubMed  PubMed Central  Google Scholar 

  • **ng D, Ma JX, Ma XL, Xu WG, Chen Y, Song DH. A meta-analysis of balloon kyphoplasty compared to percutaneous vertebroplasty for treating osteoporotic vertebral compression fractures. J Clin Neurosci. 2013;20(6):795–803.

    Article  PubMed  Google Scholar 

  • Yuan W, Cao W, Meng X, Zhu H, Liu X, Cui C, Tao L, Zhu Y. Learning curve of robot-assisted percutaneous kyphoplasty for osteoporotic vertebral compression fractures. World Neurosurg. 2020;138:e323–9.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurosurgery, IRCCS National Cancer Institute “Regina Elena”, Roma, Italy

    Stefano Telera & Laura Raus

  2. Department of Oncologic and Degenerative Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

    Valerio Pipola & Alessandro Gasbarrini

  3. Spine Surgery Department, “Maggiore” Hospital AUSL Bologna, Bologna, Italy

    Federico De Iure

Authors
  1. Stefano Telera
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Laura Raus
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Valerio Pipola
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Federico De Iure
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Alessandro Gasbarrini
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Stefano Telera .

Rights and permissions

Reprints and permissions

Copyright information

© 2021 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Telera, S., Raus, L., Pipola, V., De Iure, F., Gasbarrini, A. (2021). Vertebroplasty and Kyphoplasty: An Overview. In: Vertebral Body Augmentation, Vertebroplasty and Kyphoplasty in Spine Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-76555-2_1

Download citation

Publish with us

Policies and ethics

Search

Navigation