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Open AccessExperimental quantum homomorphic encryption
Quantum computers promise not only to outperform classical machines for certain important tasks, but also to preserve privacy of computation. For example, the blind quantum computing protocol enables secure de...
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Article
AQP5 enriches for stem cells and cancer origins in the distal stomach
LGR5 marks resident adult epithelial stem cells at the gland base in the mouse pyloric stomach1, but the identity of the equivalent human stem cell population remains unknown owing to a lack of surface markers th...
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Open AccessNeonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
Wnt signaling is critical for directing epithelial gland development within the uterine lining to ensure successful gestation in adults. Wnt-dependent, Lgr5-expressing stem/progenitor cells are essential for the ...
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Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach
The daily renewal of the corpus epithelium is fuelled by adult stem cells residing within tubular glands, but the identity of these stem cells remains controversial. Lgr5 marks homeostatic stem cells and ‘rese...
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Open AccessA quantum approach to homomorphic encryption
Encryption schemes often derive their power from the properties of the underlying algebra on the symbols used. Inspired by group theoretic tools, we use the centralizer of a subgroup of operations to present a...
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Organoids as an in vitro model of human development and disease
Barker and colleagues review the history and recent developments of organoid cultures derived from pluripotent stem cells and adult epithelia, and discuss how the technology can be used for basic research as w...
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Open AccessLaminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation
Initiation of the hair follicle placode and its subsequent growth, maturation and cycling in post-natal skin requires signaling interactions between epithelial cells and adjacent dermal cells and involves Shh ...
