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Article
AQP5 enriches for stem cells and cancer origins in the distal stomach
LGR5 marks resident adult epithelial stem cells at the gland base in the mouse pyloric stomach1, but the identity of the equivalent human stem cell population remains unknown owing to a lack of surface markers th...
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Article
Organoids as an in vitro model of human development and disease
Barker and colleagues review the history and recent developments of organoid cultures derived from pluripotent stem cells and adult epithelia, and discuss how the technology can be used for basic research as w...