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  1. No Access

    Article

    AQP5 enriches for stem cells and cancer origins in the distal stomach

    LGR5 marks resident adult epithelial stem cells at the gland base in the mouse pyloric stomach1, but the identity of the equivalent human stem cell population remains unknown owing to a lack of surface markers th...

    Si Hui Tan, Yada Swathi, Shawna Tan, Jasmine Goh, Ryo Seishima, Kazuhiro Murakami… in Nature (2020)

  2. No Access

    Article

    Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach

    The daily renewal of the corpus epithelium is fuelled by adult stem cells residing within tubular glands, but the identity of these stem cells remains controversial. Lgr5 marks homeostatic stem cells and ‘rese...

    Marc Leushacke, Si Hui Tan, Angeline Wong, Yada Swathi… in Nature Cell Biology (2017)

  3. No Access

    Article

    Lgr5 marks stem/progenitor cells in ovary and tubal epithelia

    The ovary surface epithelium (OSE) undergoes ovulatory tear and remodelling throughout life. Resident stem cells drive such tissue homeostasis in many adult epithelia, but their existence in the ovary has not ...

    Annie Ng, Shawna Tan, Gurmit Singh, Pamela Rizk, Yada Swathi… in Nature Cell Biology (2014)