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Open AccessUnderstanding the exposure risk of aerosolized Coccidioides in a Valley fever endemic metropolis
Coccidioides is the fungal causative agent of Valley fever, a primarily pulmonary disease caused by inhalation of fungal arthroconidia, or spores. Although Coccidioides has been an established pathogen for 120 ye...
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Article
Open AccessComparing telemedicine and in-person gastrointestinal cancer genetic appointment outcomes during the COVID-19 pandemic
The study purpose is to compare outcomes associated with completion of genetic testing between telemedicine and in-person gastrointestinal cancer risk assessment appointments during the COVID-19 pandemic.
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Surviving the Tides: A Study of Small-Scale Fisheries and Community Livelihoods in Selected Coastal Towns of the Western Cape, South Africa
This study explores the livelihood activities of small-scale fishers in selected coastal towns of South Africa, particularly in the Western Cape province. Small-scale fisheries are critical in supporting pover...
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A Review of Childhood Sexual Abuse Perpetration Prevention Programs
The present review examines existing childhood sexual abuse prevention programs that are focused on providing services to individuals who are at risk of perpetration. We describe several perpetrator-oriented p...
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Article
Open AccessPerceptions, knowledge, and communication preferences about indoor mold and its health implications among persons affected by Hurricane Harvey: a focus group analysis
Among people affected by Hurricane Harvey, we assessed experiences and perceptions (e.g., knowledge, attitudes, and practices) regarding mold and its impact on health and elicited participants’ opinions about ...
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Nudge with caution: targeting fruit and vegetable consumption in primary schools
Most children in the UK are not eating enough fruit and vegetables to support optimum health. Evidence-based interventions are needed to change this trend. In the present pilot study, effectiveness of simple b...
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Article
Open AccessPatient-reported outcome measures for monitoring primary care patients with depression (PROMDEP): study protocol for a randomised controlled trial
Benefits to patients from reduced depression have been shown from monitoring progress with patient-reported outcome measures (PROMs) in psychological therapy and mental health settings. This approach has not y...
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Article
Open AccessREDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: protocol for a randomised controlled trial
Around one in ten adults take antidepressants for depression in England, and their long-term use is increasing. Some need them to prevent relapse, but 30–50% could possibly stop them without relapsing and avoi...
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Conclusions
The concluding chapter reflects upon the making of metropolitan bastardy throughout the eighteenth and the first half of the nineteenth centuries. The poor law, sexuality and illegitimacy were ‘mutually consti...
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Shame
Shame has been frequently associated with unmarried parenthood. In focusing upon feelings of shame, Williams engages with the burgeoning history of emotions. This chapter explores the role played, in particula...
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The Workhouse
The eighteenth century witnessed a shift in the metropolitan landscape of plebeian childbirth with the establishment of parish workhouses and the charitable lying-in hospitals. In this chapter Williams provide...
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Punishment
The parents of illegitimate children were liable to punishment by the secular courts: mothers as ‘lewd women’ and fathers for failure to provide security and maintenance payments, as well as to the church cour...
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Introduction: Illegitimacy in London
This chapter sets out the context of unmarried parenthood in London between 1700 and 1850. Illegitimacy levels rose throughout the period and only started to decline after the mid-nineteenth century. Williams ...
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Pregnant and Birthing Bodies
Being an unmarried mother was an embodied gendered experience that started with sexual intercourse and continued to pregnancy, childbirth, and lying-in. This chapter starts by exploring courtship and sexual re...
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Maintenance
Under the bastardy laws unmarried parents, and particularly reputed fathers, were held financially responsible for their children. Putative fathers were identified and affiliated in the magistrates’ court. How...
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‘They lived together as man and wife’: Plebeian cohabitation, illegitimacy, and broken relationships in London, 1700–1840
In the early 1740s John Bell, a brewer, rented a house worth £20 a year in the parish of St Ann Blackfriars where he ‘lived and cohabited together with the said Sarah Bell [alias Morgan] as man and wife’.1 They h...
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Open AccessNrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy
Nrf2 is a key transcriptional regulator of a battery of genes that facilitate phase II/III drug metabolism and defence against oxidative stress. Nrf2 is largely regulated by Keap1, which directs Nrf2 for prote...
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Article
Open AccessLaminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation
Initiation of the hair follicle placode and its subsequent growth, maturation and cycling in post-natal skin requires signaling interactions between epithelial cells and adjacent dermal cells and involves Shh ...
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Sharing Benefits Fairly: Decision-Making and Governance
Understanding how decisions were made by the San in the Hoodia case and how decision-making and governance structures vary between bioprospectors and indigenous communities is essential for the implementation of ...
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Multidisciplinary Crisis Simulations: The Way Forward for Training Surgical Teams
High-reliability organizations have stressed the importance of nontechnical skills for safety and of regularly providing such training to their teams. Recently safety skills training has been applied in the pr...