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Article
Characteristics of Flexible Pressure Sensor According to Circuit Configuration of MWCNTs/Polydimethylsiloxane Composite and Conductive Layer
When sensors were fabricated without a conductive layer, metal wires or pin headers were mainly used to receive the electrical signals from the sensor material. By fabricating the conductive layer, the degree ...
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Article
Open AccessImproved cytosine base editors generated from TadA variants
Cytosine base editors (CBEs) enable programmable genomic C·G-to-T·A transition mutations and typically comprise a modified CRISPR–Cas enzyme, a naturally occurring cytidine deaminase, and an inhibitor of uraci...
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Article
Open AccessElliptic K3 surfaces at infinite complex structure and their refined Kulikov models
Motivated by the Swampland Distance and the Emergent String Conjecture of Quantum Gravity, we analyse the infinite distance degenerations in the complex structure moduli space of elliptic K3 surfaces. All comp...
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Article
Open AccessPhysics of infinite complex structure limits in eight dimensions
We investigate infinite distance limits in the complex structure moduli space of F-theory compactified on K3 to eight dimensions. While this is among the simplest possible arenas to test ideas about the Swampl...
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Article
Open AccessHolomorphic anomalies, fourfolds and fluxes
We investigate holomorphic anomalies of partition functions underlying string compactifications on Calabi-Yau fourfolds with background fluxes. For elliptic fourfolds the partition functions have an alternativ...
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Article
Open AccessEmergent strings from infinite distance limits
As a refinement of the Swampland Distance Conjecture, we propose that a quantum gravitational theory in an infinite distance limit of its moduli space either decompactifies, or reduces to an asymptotically ten...
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Article
Open AccessEmergent strings, duality and weak coupling limits for two-form fields
We systematically analyse weak coupling limits for 2-form tensor fields in the presence of gravity. Such limits are significant for testing various versions of the Weak Gravity and Swampland Distance Conjectur...
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Article
Electronic states of graphene quantum dots induced by nanobubbles
We analyze the effects of the strain-induced pseudo-magnetic fields (PMFs) originating from nanobubbles (NBs) to examine the possibility for a graphene quantum dot (QD) created by strain engineering. We study ...
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Article
Open AccessQuantum corrections in 4d N = 1 infinite distance limits and the weak gravity conjecture
We study quantum corrections in four-dimensional theories with N = 1 supersymmetry in the context of Quantum Gravity Conjectures. According to the Emergent String Conjecture, infinite distance limits in quantum g...
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Article
Open AccessQuasi-Jacobi forms, elliptic genera and strings in four dimensions
We investigate the interplay between the enumerative geometry of Calabi-Yau fourfolds with fluxes and the modularity of elliptic genera in four-dimensional string theories. We argue that certain contributions ...
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Article
Open AccessThe trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
Efficient search for DNA damage embedded in vast expanses of the DNA genome presents one of the greatest challenges to DNA repair enzymes. We report here crystal structures of human 8-oxoguanine (oxoG) DNA gly...
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Article
Directed evolution of adenine base editors with increased activity and therapeutic application
The foundational adenine base editors (for example, ABE7.10) enable programmable A•T to G•C point mutations but editing efficiencies can be low at challenging loci in primary human cells. Here we further evolv...
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Article
Open AccessCytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Cytosine base editors (CBEs) enable efficient, programmable reversion of T•A to C•G point mutations in the human genome. Recently, cytosine base editors with rAPOBEC1 were reported to induce unguided cytosine ...
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Article
Open AccessModular fluxes, elliptic genera, and weak gravity conjectures in four dimensions
We analyse the Weak Gravity Conjecture for chiral four-dimensional F-theory compactifications with N = 1 supersymmetry. Extending our previous work on nearly tensionless heterotic strings in six dimensions, we sh...
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Article
Open AccessAngiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease
MYH9, a widely expressed gene encoding nonmuscle myosin heavy chain, is also expressed in podocytes and is associated with glomerular pathophysiology. However, the mechanisms underlying MYH9-related glomerular...
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Article
Correlation of antibacterial and time resolved photoluminescence studies using bio-reduced silver nanoparticles conjugated with fluorescent quantum dots as a biomarker
This report lays the foundation stone for the real time detector to control and monitor antibiotic resistant bacteria’s. To start with, firstly, the green synthesis of silver nanoparticles were done by the bio...
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Article
NMR 1H,13C, 15N resonance assignment of the G12C mutant of human K-Ras bound to GppNHp
K-Ras exists in two distinct structural conformations specific to binding of GDP and GTP nucleotides. The cycling between an inactive, GDP-bound state and an active, GTP-bound state is regulated by guanine nuc...
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Article
Effect of Isovalent Do** on the Magnetic Properties of ZnMnO Diluted Magnetic Semiconductors
The magnetic properties of a ZnMnO diluted magnetic semiconductor isovalently doped with Mg and S have been successfully studied. ZnMnO alloys were prepared with different concentrations of magnesium and sulfu...
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Article
Open Access6d SCFTs and U(1) flavour symmetries
We study the behaviour of abelian gauge symmetries in six-dimensional N = (1,0) theories upon decoupling gravity and investigate abelian flavour symmetries in the context of 6d N = (1, 0) SCFTs. From a supergravi...
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Article
Open AccessTensionless strings and the weak gravity conjecture
We test various conjectures about quantum gravity for six-dimensional string compactifications in the framework of F-theory. Starting with a gauge theory coupled to gravity, we analyze the limit in Kähler modu...
