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  1. Article

    Open Access

    Nutrient levels control root growth responses to high ambient temperature in plants

    Global warming will lead to significantly increased temperatures on earth. Plants respond to high ambient temperature with altered developmental and growth programs, termed thermomorphogenesis. Here we show th...

    Sanghwa Lee, Julia Showalter, Ling Zhang, Gaëlle Cassin-Ross in Nature Communications (2024)

  2. No Access

    Protocol

    Assessing Temperature Responses in Roots

    Due to global warming, it is important to understand how plants respond to high ambient temperature. Plant growth responses to high ambient temperature are termed thermomophogenesis and have been explored for ...

    Sanghwa Lee, Wolfgang Busch in Thermomorphogenesis (2024)

  3. No Access

    Protocol

    Characterization of PIF4 Phosphorylation by SPA1

    The PHYTOCHROME INTERACTING FACTORs (PIFs) play pivotal roles in regulating thermo- and photo-morphogenesis in Arabidopsis. One of the main hubs in thermomorphogenesis is PIF4, which regulates plant development u...

    Sanghwa Lee, Enamul Huq in Thermomorphogenesis (2024)

  4. No Access

    Article

    Stretchable colour-sensitive quantum dot nanocomposites for shape-tunable multiplexed phototransistor arrays

    High-performance photodetecting materials with intrinsic stretchability and colour sensitivity are key requirements for the development of shape-tunable phototransistor arrays. Another challenge is the proper ...

    Jun-Kyul Song, Junhee Kim, Jiyong Yoon, Ja Hoon Koo, Hyun** Jung in Nature Nanotechnology (2022)

  5. No Access

    Article

    Nano-biomarker-Based Surface-Enhanced Raman Spectroscopy for Selective Diagnosis of Gallbladder and Liver Injury

    During living donor liver transplantation, a number of blood vessels and bile ducts are anastomosed while the liver and gallbladder are resected in the donor and recipient. Early detection and treatment of com...

    Sanghwa Lee, Eunyoung Tak, Yu Jeong Cho, Jiye Kim, Jooyoung Lee in BioChip Journal (2022)

  6. Article

    Open Access

    Spatial regulation of thermomorphogenesis by HY5 and PIF4 in Arabidopsis

    Plants respond to high ambient temperature by implementing a suite of morphological changes collectively termed thermomorphogenesis. Here we show that the above and below ground tissue-response to high ambient...

    Sanghwa Lee, Wenli Wang, Enamul Huq in Nature Communications (2021)

  7. No Access

    Article

    Highly luminescent and catalytically active suprastructures of magic-sized semiconductor nanoclusters

    Metal chalcogenide magic-sized nanoclusters have shown intriguing photophysical and chemical properties, yet ambient instability has hampered their extensive applications. Here we explore the periodic assembly...

    Woonhyuk Baek, Megalamane S. Bootharaju, Kelly M. Walsh, Sanghwa Lee in Nature Materials (2021)

  8. No Access

    Chapter

    Label-Free Raman Spectroscopic Techniques with Morphological and Optical Characterization for Cancer Cell Analysis

    Using the Raman spectroscopic analysis system that gives the chemical information of the biomaterials, classification is performed through the acquisition of fingerprint signals for each cell line, and the bas...

    Sanghwa Lee, Jun Ki Kim in Advanced Imaging and Bio Techniques for Convergence Science (2021)

  9. Article

    Open Access

    Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly

    In neuronal exocytosis, SNARE assembly into a stable four-helix bundle drives membrane fusion. Previous studies have revealed that the SM protein Munc18-1 plays a critical role for precise SNARE assembly with ...

    Sanghwa Lee, Jonghyeok Shin, Younghun Jung, Hey** Son, Jaeil Shin in Scientific Reports (2020)

  10. Article

    Open Access

    Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effect of androgen in cultured human dermal papilla cells

    Dermal papilla cells (DPCs) play a key role in hair growth among the various cell types in hair follicles. Especially, DPCs determine the fate of hair follicle such as anagen to telogen transition and play a p...

    Jae Young Shin, Yun-Ho Choi, Jaeyoon Kim in BMC Complementary Medicine and Therapies (2020)

  11. Article

    Open Access

    Direct observation of DNA target searching and cleavage by CRISPR-Cas12a

    Cas12a (also called Cpf1) is a representative type V-A CRISPR effector RNA-guided DNA endonuclease, which provides an alternative to type II CRISPR–Cas9 for genome editing. Previous studies have revealed that ...

    Yongmoon Jeon, You Hee Choi, Yunsu Jang, Jihyeon Yu, Jiyoung Goo in Nature Communications (2018)

  12. Article

    Open Access

    Micro-hydrogel Particles Consisting of Hyperbranched Polyamidoamine for the Removal of Heavy Metal Ions from Water

    A series of micro-hydrogel particles consisting of hyperbranched polyamidoamine (HPAMAM) without any supporting core materials was synthesized via the inverse suspension condensation polymerization of A2 and B4 m...

    Sanghwa Lee, Youngsik Eom, Jeyoung Park, **hee Lee, Sang Youl Kim in Scientific Reports (2017)

  13. Article

    Open Access

    Molecular mechanisms of atlastin-mediated ER membrane fusion revealed by a FRET-based single-vesicle fusion assay

    Homotypic fusion of endoplasmic reticulum membranes is driven by atlastin GTPases; however, the underlying mechanism remains largely unknown. Here, using a FRET-based single-vesicle fusion assay with liposomes...

    Kyung Tae Kim, Yeo** Moon, Yunsu Jang, Kang Taek Lee, Changwook Lee in Scientific Reports (2017)

  14. No Access

    Article

    Development of a data-mining methodology for spent nuclear fuel forensics

    The purpose of this study is to categorize the type of spent nuclear fuels using simulation data-based classification methods. Considering the practical conditions making the full analysis of radioactive nucli...

    Sanghwa Lee, Kyungho **, Jaekwang Kim in Journal of Radioanalytical and Nuclear Che… (2017)

  15. No Access

    Chapter and Conference Paper

    Classification Methodologies for Nuclear Spent Fuel Forensic

    The purpose of this study is to estimate the burning history of spent nuclear fuel using statistical data mining. The fuel history is characterized by burn-up, enrichment and cooling time, which are termed as ...

    Sanghwa Lee, Seungmin Lee, Gyunyoung Heo in Proceedings of The 20th Pacific Basin Nucl… (2017)

  16. No Access

    Article

    Induction and control of supramolecular chirality by light in self-assembled helical nanostructures

    Evolution of supramolecular chirality from self-assembly of achiral compounds and control over its handedness is closely related to the evolution of life and development of supramolecular materials with desire...

    Jisung Kim, **hee Lee, Woo Young Kim, Hyungjun Kim, Sanghwa Lee in Nature Communications (2015)

  17. No Access

    Article

    Microscopic analysis of thermally-driven formation of Cu-Si alloy nanoparticles in a Cu/Si template

    Selective thermal diffusion of Cu into a 100-nm-thick SiO2-patterned Si(001) substrate was investigated to elucidate the spontaneous formation of Cu-Si alloy nanoparticles. Transmission electron microscopy and en...

    Wooyoung Lee, Miyeon Jue, Sanghwa Lee in Journal of the Korean Physical Society (2013)

  18. No Access

    Article

    A single-molecule dissection of ligand binding to a protein with intrinsic dynamics

    Proteins that sample multiple conformations in the absence of a ligand have been presumed to operate via a conformational selection mechanism. Single molecule FRET studies of maltose binding protein now cast d...

    Eunkyung Kim, Sanghwa Lee, Aram Jeon, Jung Min Choi in Nature Chemical Biology (2013)