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Article
Medium Chain Length Polyhydroxyalkanoate Production by Engineered Pseudomonas gessardii Using Acetate-formate as Carbon Sources
Production of medium chain length polyhydroxyalkanoate (mcl-PHA) was attempted using Pseudomonas gessardii NIBRBAC000509957, which was isolated from Sunchang, Jeollabuk-do, Republic of Korea (35°24′27.7"N, 127°09...
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Article
Uncoupling nanoparticle geometry from material properties for improved hole injection at submonolayer nanoparticle electrode interlayers in organic hole-only devices
We demonstrate enhanced hole injection into organic hole transport layers (HTL) from submonolayer NiOx, SnOx, and LiF nanoparticle hole injection layers (HIL) produced using reverse micelle templating. Decoration...
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Article
Open AccessQuasi-seamless stitching for large-area micropatterned surfaces enabled by Fourier spectral analysis of moiré patterns
The main challenge in preparing a flexible mold stamp using roll-to-roll nanoimprint lithography is to simultaneously increase the imprintable area with a minimized perceptible seam. However, the current metho...
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Article
Open AccessScreening of the siGPCR library in combination with cisplatin against lung cancers
The screening of siRNAs targeting 390 human G protein-coupled receptors (GPCRs) was multiplexed in combination with cisplatin against lung cancer cells. While the cell viability measure hardly captured the ant...
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Article
Elimination of solidification shrinkage defects in the casting of aluminum alloy
In this study, the analysis is carried out to optimize in-gate position and size of riser for casting mold. The baseline size of riser for the casting of boat propeller is based on geometric modulus and therma...
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Article
Open AccessConstruction of a tunable promoter library to optimize gene expression in Methylomonas sp. DH-1, a methanotroph, and its application to cadaverine production
As methane is 84 times more potent than carbon dioxide in exacerbating the greenhouse effect, there is an increasing interest in the utilization of methanotrophic bacteria that can convert harmful methane into...
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Article
Drone-Based Three-Dimensional Photogrammetry and Concave Hull by Slices Algorithm for Apple Tree Volume Map**
Apple tree volume is an important factor in apple quality control and spraying strategies. The measurement is a laborious task because of the complex structure of the apple tree. This study developed a technol...
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Article
Introduction of an AU-rich Element into the 5’ UTR of mRNAs Enhances Protein Expression in Escherichia coli by S1 Protein and Hfq Protein
AU-rich elements in 5’ untranslated region (UTR) are known to increase translation efficiency by recruiting S1 protein that facilitates the assembly of ribosomes. However, AU-rich elements also serve a binding...
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Article
Open AccessA novel synthetic microtubule inhibitor exerts antiproliferative effects in multidrug resistant cancer cells and cancer stem cells
The success of cancer chemotherapy is limited by multidrug resistance (MDR), which is mainly caused by P-glycoprotein (P-gp) overexpression. In the present study, we describe a novel microtubule inhibitor, 5-(N-m...
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Article
Open AccessLung retention and particokinetics of silver and gold nanoparticles in rats following subacute inhalation co-exposure
Inhalation exposure to nanomaterials in workplaces can include a mixture of multiple nanoparticles. Such ambient nanoparticles can be of high dissolution or low dissolution in vivo and we wished to determine w...
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Article
Necessity of submonolayer LiF anode interlayers for improved device performance in blue phosphorescent OLEDs
Lithium fluoride (LiF) is a widely used interlayer in organic optoelectronic devices, at both top and bottom electrodes, with various mechanisms proposed for its effectiveness at each interface. Here we examin...
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Article
Open AccessChloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer
Overcoming drug-resistance is a big challenge to improve the survival of patients with epithelial ovarian cancer (EOC). In this study, we investigated the effect of chloroquine (CQ) and its combination with ci...
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Article
Open AccessPreclinical assessment of the VEGFR inhibitor axitinib as a therapeutic agent for epithelial ovarian cancer
Axitinib, small molecule tyrosine kinase inhibitor, demonstrates anti-cancer activity for various solid tumors. We investigated anti-cancer effect of axitinib in epithelial ovarian cancer (EOC). We treated EOC...
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Article
The effect of body position on airway patency in obstructive sleep apnea: CT imaging analysis
Positional change during sleep influences upper airway patency. However, few studies have used imaging techniques to demonstrate the change. This study aims to determine the effect of positional change on the ...
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Article
Open AccessImproved hole injection for blue phosphorescent organic light-emitting diodes using solution deposited tin oxide nano-particles decorated ITO anodes
Blue phosphorescent organic light-emitting diodes (PHOLEDs) were fabricated with tin oxide (SnOx) nano-particles (NPs) deposited at the ITO anode to improve their electrical and optical performances. SnOx NPs hel...
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Article
Therapeutic targeting of lipid synthesis metabolism for selective elimination of cancer stem cells
Cancer stem cells (CSCs) are believed to have an essential role in tumor resistance and metastasis; however, no therapeutic strategy for the selective elimination of CSCs has been established. Recently, severa...
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Article
β-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer
The availability of large-scale drug screening data on cell line panels provides a unique opportunity to identify predictive biomarkers for targeted drug efficacy. Analysis of diverse drug data on ~990 cancer ...
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Article
Open AccessQuantitative Analysis of Charge Distribution in Bi-Emissive layer White Organic Light-Emitting Diodes with Two Fluorescent Dopants
This work seeks to establish a quantitative method which can estimate the holes and electrons ratio in the emission zones. We fabricated multilayered white organic light-emitting diodes (WOLEDs) with the devic...
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Article
Open AccessCardiac glycosides display selective efficacy for STK11 mutant lung cancer
Although STK11 (LKB1) mutation is a major mediator of lung cancer progression, targeted therapy has not been implemented due to STK11 mutations being loss-of-function. Here, we report that targeting the Na+/K+-AT...
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Article
Electrically Insulative Performances of Ceramic and Clay Films Deposited via Supersonic Spraying
Supersonic spray coating techniques were applied to deposit ceramic and clay particles as films for use in electrical insulation. TiO2 and Al2O3 ceramics were aerosol-deposited under vacuum while kaolinite, montm...
