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Article
Open AccessTranscription factor FoxO1 regulates myoepithelial cell diversity and growth
Salivary gland myoepithelial cells regulate saliva secretion and have been implicated in the histological diversity of salivary gland tumors. However, detailed functional analysis of myoepithelial cells has no...
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Protocol
Isolation and Functional Analysis of Myoepithelial Cells from Adult Mouse Submandibular Glands
Salivary gland myoepithelial cells regulate salivary secretion and have been implicated in the histological diversity of salivary gland tumors. However, isolation of myoepithelial cells has been difficult owin...
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Article
Author Correction: Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication
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Article
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication
Salivary glands act as virus reservoirs in various infectious diseases and have been reported to be targeted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the mechanisms underlying ...
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Article
Open AccessIn vitro monitoring of HTR2A-positive neurons derived from human-induced pluripotent stem cells
The serotonin 5-HT2A receptor (5-HT2AR) has been receiving increasing attention because its genetic variants have been associated with a variety of neurological diseases. To elucidate the pathogenesis of the neur...
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Article
Open AccessPublisher Correction: Massively parallel sequencing of cell-free DNA in plasma for detecting gynaecological tumour-associated copy number alteration
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessGeneration of orthotopically functional salivary gland from embryonic stem cells
Organoids generated from pluripotent stem cells are used in the development of organ replacement regenerative therapy by recapitulating the process of organogenesis. These processes are strictly regulated by m...
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Article
Open AccessMassively parallel sequencing of cell-free DNA in plasma for detecting gynaecological tumour-associated copy number alteration
The discovery of circulating tumour DNA molecules created a paradigm shift in tumour biomarkers as predictors of recurrence. Non-invasive prenatal testing (NIPT) to detect circulating cell-free foetal DNA in m...
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Article
Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependent manner
Osteoarthritis is a degenerative joint disease caused by excessive death of chondrocytes and loss of the extracellular matrix (ECM) in articular cartilage. We previously reported that reactive oxygen species (...
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Chapter and Conference Paper
Generation of Rac1 conditional mutant mice by Cre/loxP system
Rac1 is a small GTPase which belongs to the Rho family of proteins, and has multiple roles in cellular function, including actin cytoskeleton organization, transcriptional activation, microtubule formation, an...
