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Article
Multiplicative effect of inhaled plutonium oxide and benzo (a) pyrene on lung carcinogenesis in rats
This study describes the effect of intratracheal instillations (2 X 5 mg) of benzo(a)pyrene (B(a)P) on lung carcinogenesis in rats which had previously inhaled different levels of 239 plutonium oxide (220, 630...
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Effect of Chronic Administration of a Synthetic Aromatic Retinoid (Ro 10-9359) on the Development of Lung Squamous Metaplasia and Epidermoid Cancer in Rats
Since the first studies of Saffioti et al. (1) suggesting the preventive effect of high doses of vitamin A on squamous metaplasias of trachea and bronchis, several authors have used synthetic analogs of vitami...
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Article
Bronchoconstriction induced by intratracheal administration of platelet-activating factor (PAF-acether) in baboons
Intratracheal administration of PAF-acether (60 μg.kg−1) was performed in six premedicated, curarized and mechanically ventilated baboons. Whereas intratracheal administration of an equal amount of solvent (200μl...
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Article
Bone tumours induced in rats with radioactive cerium
A technique is described for the induction of metastasizing bone tumours in rats by local inoculation of 144cerium. Bone sarcomas develop in 90% of the animals and 74% of these had lung metastases. The tumours...
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Article
Complete or almost complete analogy of chromosome banding between the baboon (Papio papio) and man
The karyotype of the baboon (Papio papio) was studied using several staining techniques: Q bands, R bands, T bands, C bands, G 11.6 bands, and after incorporation of BrdU. When compared with the karyotypes of the...