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Article
115 Blood Sugar Monitoring in Preterm Infants < 31 Weeks and < 1000 G
BACKGROUND: Glucose values <2.7 mmol/l >48h or on >5 occasions lead to neurological deficits. Bedside glucose measurement devices are inaccurate. AIM: To determine whether frequent random blood sugar (BS) meas...
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Article
Changes in the apparent diffusion coefficient of water (ADC) and phosphocreatine to inorganic phosphate ratio (PCr/Pi) in newborn pigs following hypoxia-ischaemia (HI)
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Article
Cerebral hyperaemia following hypoxic-ischaemic injury injury in the anaesthetised, newborn piglet
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Article
Proton Magnetic Resonance Spectroscopy of the Brain during Acute Hypoxia-Ischemia and Delayed Cerebral Energy Failure in the Newborn Piglet
Studies of the brains of severely birth-asphyxiated infants using proton(1H) magnetic resonance spectroscopy (MRS) have shown changes indicating a rise in cerebral lactate (Lac) and a fall in N- acetylaspartate (...
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Article
Mild Hypothermia after Severe Transient Hypoxia-Ischemia Reduces the Delayed Rise in Cerebral Lactate in the Newborn Piglet
This study tested the hypothesis that mild hypothermia after severe transient hypoxia-ischemia reduces the subsequent delayed rise in cerebral lactate peak-area ratios as determined by proton (1H) magnetic resona...
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Article
Magnesium Sulfate after Transient Hypoxia-Ischemia Fails to Prevent Delayed Cerebral Energy Failure in the Newborn Piglet
Severely birth-asphyxiated human infants develop delayed(“secondary”) cerebral energy failure, which carries a poor prognosis, during the first few days of life. This study tested the hypothesis that i.v. magn...
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Article
Proton Magnetic Resonance Spectroscopy of the Brain in Normal Preterm and Term Infants, and Early Changes after Perinatal Hypoxia-Ischemia
The aims of this study were 1) to define normal perinatal maturational changes in proton metabolite peak-area ratios in two regions of the neonatal brain, the thalamic and occipitoparietal regions, and2) to inves...