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Article
Severe RAS-Associated Lymphoproliferative Disease Case with Increasing αβ Double-Negative T Cells with Atypical Features
Autoimmune lymphoproliferative syndrome (ALPS) is a disease of lymphocyte homeostasis caused by FAS-mediated apoptotic pathway dysfunction and is characterized by non-malignant lymphoproliferation with an incr...
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Article
A short-term three dimensional culture-based drug sensitivity test is feasible for malignant bone tumors
The feasibility of a short-term, three-dimensional (3D) culture–based drug sensitivity test (DST) for surgically resected malignant bone tumors, including osteosarcoma (OS), was evaluated utilizing two OS cell...
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Article
Open AccessInfantile hepatic hemangioma and hepatic mesenchymal hamartoma in an infant associated with placental mesenchymal dysplasia: a case report
Although infantile hepatic hemangioma and hepatic mesenchymal hamartoma are relatively common in benign pediatric liver tumors, coexistence of the two tumors is rare. Placental mesenchymal dysplasia is also a ...
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Article
A novel method for isolating lymphatic endothelial cells from lymphatic malformations and detecting PIK3CA somatic mutation in these isolated cells
Tissue disaggregation and the cell sorting technique by surface markers has played an important role in isolating lymphatic endothelial cells (LECs) from lymphatic malformation (LM). However, this technique ma...
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Chapter
Long-Term Functional Outcome and Quality of Life After Kasai Operation
The Japanese Biliary Atresia Registry reported that 10-year and 20-year native liver survival rates were 55% and 49%, respectively. An increasing number of patients with biliary atresia have now survived into ...
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Article
Lymphatic malformations compromising the upper airway in children: ultrasound-guided intralesional focal sclerotherapy with bleomycin targeting culprit lesions
Lymphatic malformations (LMs) compromising the upper airway is a life-threatening and intractable disease. Here, we establish a novel method to perform intralesional focal sclerotherapy targeting the culprit f...
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Chapter
Surgical Treatment and Its Prognosis for Extra-lobar Pulmonary Sequestration Without Foregut Communication
Extra-lobar pulmonary sequestration (ELS) has a broad spectrum of clinical manifestations. When symptomatic, open or endoscopic sequestrectomy is indicated for its treatment with little objection. When asympto...
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Chapter
Complications
The majority of patients with Hirschsprung’s disease have an excellent postoperative outcome after definitive surgeries, i.e. classical pull-through procedures and contemporarily well-received minimally invasi...
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Article
Open AccessContinuous transanal decompression for infants with long- and total-type Hirschsprung’s diseases as a bridge to curative surgery: a single-center experience
The purpose of this study is to assess the usefulness of continuous bowel decompression using an indwelling transanal tube (ITT) for preoperative management in infants with long-segment (L)- or total (T)-type ...
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Article
Usefulness of a recanalized umbilical vein for vascular reconstruction in pediatric hepatic surgery
Pediatric surgeons currently engage in various abdominal vascular surgeries, which sometimes require vascular conduits or grafts. Herein, we report our experience with patients undergoing vascular reconstructi...
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Chapter
Application of Indocyanine Green Fluorescence Imaging to Pediatric Hepatoblastoma Surgery
We will elaborate on navigation surgery using indocyanine green (ICG) fluorescence imaging in pediatric hepatoblastoma. Chemotherapy is effective against hepatoblastoma, and while complete surgical resection o...
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Article
Impact of an external lengthening procedure on the outcome of long-gap esophageal atresia at our hospitals
To demonstrate the outcome of external lengthening for long-gap esophageal atresia (LGEA) at our hospitals.
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Article
A case of alpha-fetoprotein-producing gastric cancer in a child presenting with rupture of multiple liver metastases
We report a 14-year-old boy with alpha-fetoprotein-producing gastric cancer (AFPGC) who was found with ruptured metastatic tumor in the liver. AFPGC is exceedingly rare in pediatric age. It often shows metasta...
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Article
Navigation using indocyanine green fluorescence imaging for hepatoblastoma pulmonary metastases surgery
To achieve precise and sensitive detection of chemotherapy-resistant hepatoblastoma pulmonary metastases, we performed surgery using indocyanine green (ICG) fluorescence imaging navigation. Lung metastasectomi...
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Article
Type IV laryngotracheoesophageal cleft repair by a new combination of lateral thoraco-cervical and laryngoscopic approaches
Type IV laryngotracheoesophageal cleft (LTEC) is a rare congenital anomaly that is associated with high morbidity and mortality despite various forms of surgical repair. This article presents our strategy for ...
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Article
Recanalized umbilical vein as a conduit for mesenterico/porto-Rex bypass for patients with extrahepatic portal vein obstruction
Mesenterico-left portal vein (meso-Rex) bypass is as an effective modality for restoring intrahepatic portal perfusion in patients with extrahepatic portal vein obstruction. Achieving sufficient patency is dif...
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Article
Anorectal malformation associated with a perineal protrusion of the rectal mucosa: case presentation
We present a rare case of a female neonate with an imperforate anus associated with a perineal mass which may correspond to an extrophied rectal duplication. Associated anomalies were thoracic hemivertebrae an...
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Article
Biliary rhabdomyosarcoma
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Article
Aplasia of the dorsal pancreas and choledochal cyst
The authors describe a rare case of choledochal cyst and aplasia of the dorsal pancreas complicated with chronic pancreatitis. A 9-year-old boy presented with obstructive jaundice. After biliary drainage using...
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Article
Pericardial hemangioma presenting fetal cardiac tamponade and postnatal bronchostenosis
A case of pericardial hemangioma is described which was resected in the neonatal period due to its effect on the cardiopulmonary system. Preoperative differential diagnosis of a teratoma was difficult. Surgica...