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Long-Term Functional Outcome and Quality of Life After Kasai Operation

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Introduction to Biliary Atresia

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Abstract

The Japanese Biliary Atresia Registry reported that 10-year and 20-year native liver survival rates were 55% and 49%, respectively. An increasing number of patients with biliary atresia have now survived into adulthood with their native livers, achieving normal physical growth, favorable liver function, near-normal neurodevelopment, and social performances. However, more than half of these patients have had liver-related complications such as portal hypertension and cholangitis, which can be a risk factor for requiring liver transplantation (LT) and impairing health-related quality of life (QOL). Therefore, life-long meticulous follow-up is mandatory in order to promote health and QOL, deal with sequelae and/or complications appropriately, as well as to determine the optimal timing of LT.

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  1. Kanagawa Children’s Medical Center, Yokohama, Japan

    Masato Shinkai, Norihiko Kitagawa, Kyoko Mochizuki & Hidehito Usui

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  2. Norihiko Kitagawa
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Correspondence to Masato Shinkai .

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  1. Department of Pediatric Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan

    Masaki Nio

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Shinkai, M., Kitagawa, N., Mochizuki, K., Usui, H. (2021). Long-Term Functional Outcome and Quality of Life After Kasai Operation. In: Nio, M. (eds) Introduction to Biliary Atresia. Springer, Singapore. https://doi.org/10.1007/978-981-16-2160-4_38

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