68 Result(s)
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Muhammad Nawaz Tahir
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Article
A Dual Methodology Comprising Experimental and Theoretical Techniques to Study the Synthesis, Characterization, and Supramolecular Assembly of Schiff Bases Derived from Benzocaine
Benzocaine is known for its antibacterial, anticancer, antitumor, and antifungal properties. Herein, a series of three new Schiff bases is synthesized by reacting benzocaine with salicylaldehyde (E4AS), 2,3-dihyd...
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Article
A copper(II) chloride coordination compound with 2-phenyl-4,5-dihydro-1H-imidazole ligand: synthesis, characterization, crystal structure, HSA, and DFT studies
Under ultrasound irradiation in an ethanol solvent, a new coordination complex of Cu(II) was successfully synthesized within a 10-min timeframe through the treatment of an imidazole-based ligand (PDI) with a c...
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Article
Synthesis, Structural Elucidation and DNA-Binding Studies of Centrosymmetric Paddlewheel Copper Carboxylate Complexes
Synthesis, characterization and structural relevance of four new copper carboxylate complexes (1–4) has been presented here. The complexes have been synthesized by direct treatment of the substituted phenyl aceta...
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Article
Ultrasound irradiation synthesis of novel copper(II) complex with the 2-thiophenimidazoline ligand: SC-XRD, HSA, and DFT study
A novel coordination CuCl2(L)2 complex was synthesized by complexation of the 2-thiophenimidazoline ligand with CuCl2.2H2O in less than 10 min. The synthesis was done using ultrasound irradiation in an ethanol so...
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Article
Docking, DFT, and structural study of N-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamothioyl)benzamide
In the current work, we report the synthesis and characterization of N-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamothioyl)benzamide by reacting 4-aminoantipyrine and benzoylisothiocynate i...
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Article
Crystal structure, supramolecular assembly exploration by Hirshfeld surface analysis and DFT inspection of the synthesized functionalized crystalline anilide
The current research work is about the synthesis of functionalized crystalline anilide, i.e., (Z)-4-((2-nitrophenyl)amino)-4-oxobut-2-enoic acid (NAOB) and its experimental and theoretical investigation. The sing...
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Article
Structural and computational analysis, spectroscopic and electrochemical elucidation of a Schiff base
Schiff base 4-(((3-(trifluoromethyl)phenyl)imino)methyl)phenol (TPP) was successfully synthesized and characterized by FT-IR, NMR and SC-XRD. Crystal analysis pointed up the presence of two crystallographicall...
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Article
Synthesis and antioxidant screening of Novel indole amines
Novel indoles amines have been synthesized and screened for antioxidant activity. Chiron approach is used to synthesis enantiopure heterocycles. Newly synthesized indole amines showed good antioxidant potentia...
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Article
Single crystal inspection, Hirshfeld surface investigation and DFT study of a novel derivative of 4-fluoroaniline: 4-((4-fluorophenyl)amino)-4-oxobutanoic acid (BFAOB)
The title compound, C10H10FNO3, also known as [4-((4-fluorophenyl)amino)-4-oxobutanoic acid] (BFAOB), is synthesized efficiently, and its structure is confirmed by the SC-XRD technique, which indicates that two c...
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Article
Open AccessSynthesis, crystal structure, Hirshfeld surface investigation and comparative DFT studies of ethyl 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate
The ethyl 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate (1), a thiazole ester, was synthesized by refluxing 1-(2-nitrobenzylidene)thiosemicarbazide and ethyl bromopyruvate. The compound is characteri...
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Article
Open AccessHigh-throughput synthesis of CeO2 nanoparticles for transparent nanocomposites repelling Pseudomonas aeruginosa biofilms
Preventing bacteria from adhering to material surfaces is an important technical problem and a major cause of infection. One of nature’s defense strategies against bacterial colonization is based on the biohal...
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Article
Structural characterization and antileishmanial activity of newly synthesized organo-bismuth(V) carboxylates: experimental and molecular docking studies
In a quest to discover new formulations for the treatment of various parasitic diseases, a series of heteroleptic triorganobismuth(V) biscarboxylates of type [BiR3(O2CR′)2], where R=C6H5 for 1–4 and p-CH3C6H4 for...
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Article
Nickel(II), copper(II) and zinc(II) complexes containing symmetrical Tetradentate Schiff base ligand derived from 3,5-diiodosalicylaldehyde: Synthesis, characterization, crystal structure and antimicrobial activity
Novel transition metal complexes of nickel(II), copper(II) and zinc(II) with a symmetrical tetradentate Schiff base, obtained by condensation of 1,3-diaminopropane and 3,5-diiodosalicylaldehyde, N,N′-bis(3,5-d...
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Article
Selective oxidation of benzyl alcohols to benzaldehydes catalyzed by dioxomolybdenum Schiff base complex: synthesis, spectral characterization, crystal structure, theoretical and computational studies
A novel dioxomolybdenum Schiff base complex, MoO2L·DMF, was synthesized by treating MoO2(acac)2 with an ONO donor Schiff base ligand (H2L) derived by the condensation of 4-aminobenzohydrazide and 3-methoxysalicyl...
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Article
Designing, spectroscopic and structural characterization and evaluation of biological potential as well as molecular docking studies of Zn(II)-based metallo-pharmaceuticals
Six new Zn(II) carboxylates derived from 2-(3-chlorophenyl) acetic acid, 2-(2-chlorophenyl) acetic acid and 2-(2-methoxy phenyl) acetic acid were synthesized and characterized by FTIR, multinuclear NMR (1H and 13
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Article
Esterification of Salicylic acid with Succinylated Dextran Using ZrOCl2.8H2O over MCM-41: A Novel Strategy to Design Polysaccharide-Based Macromolecular Prodrugs
We are exploiting the use of a versatile catalyst taken from heterogeneous catalysis, i.e., ZrOCl2.8H2O to efficiently catalyze the reaction of dextran-succinate conjugate (Dex-SAn) with salicylic acid (SA) under...
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Article
Synthesis of novel organotin(IV) complex for multiple applications: as biologically potent and single molecular precursor
This work reports a facile solution-based synthesis of novel single molecular precursor (SMP), triphenylstannyl 4-((4-bromophenyl) amino)-4-oxobut-2-enoate complex (2). The as-prepared SMP was characterized by...
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Article
Synthesis, single-crystal X-ray diffraction, and in vitro biological evaluation of sodium, cobalt, and tin complexes of o-nitro-/o-methoxyphenylacetic acid: experimental and theoretical investigation
Four new metal carboxylates with o-nitro- and o-methoxyphenylacetic acid were synthesized and well characterized using single-crystal XRD. The synthesized complexes were evaluated for their biological potentials ...
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Article
Cancer Chemopreventive and Cytotoxic Activities of Isowithametelin from Datura innoxia
Datura innoxia Mill., Solanaceae, an underexplored ethnomedicinal plant, has been empirically evaluated in the current study for the isolation of bioactive agents. A crude extract of D. innoxia leaves was subject...
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Article
Synthesis of hierarchically organized α-Fe2O3 nanostructures for the photocatalytic degradation of methylene blue
The solvothermal synthesis of hierarchically organized hematite nanoparticles is reported. The nanoparticles with an average diameter of ≈ 55 nm consist of self-assembled small sub-particles with average sizes...
