46 Result(s)

Article

Diagnosing sepsis: where we’re at and where we’re going

Tobias Zimmermann, David Brealey, Mervyn Singer in Intensive Care Medicine (2024)

Article

2030: The need for microbiologists and antimicrobial stewardship teams will still remain paramount. Author’s reply

Ines Lakbar, Mervyn Singer, Marc Leone in Intensive Care Medicine (2023)

Article

2030: will we still need our microbiologist?

Ines Lakbar, Mervyn Singer, Marc Leone in Intensive Care Medicine (2023)

Article

Trials on oxygen targets in the critically ill patients: do they change our knowledge and practice?

Massimo Girardis, Angelique M. E. de Man, Mervyn Singer in Intensive Care Medicine (2023)

Article

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered as indicators of either infection or dysregulated ...

Pedro Póvoa, Luís Coelho, Felipe Dal-Pizzol, Ricard Ferrer… in Intensive Care Medicine (2023)

Article

Understanding post-COVID-19 interstitial lung disease (ILD): a new fibroinflammatory disease entity

Puja Mehta, Ivan O. Rosas, Mervyn Singer in Intensive Care Medicine (2022)

Article

High oxygen level in traumatic brain injury patients. Never ending story?

Karim Asehnoune, Fabio S. Taccone, Mervyn Singer in Intensive Care Medicine (2022)

Article

Presymptomatic diagnosis of postoperative infection and sepsis using gene expression signatures

Early accurate diagnosis of infection ± organ dysfunction (sepsis) remains a major challenge in clinical practice. Utilizing effective biomarkers to identify infection and impending organ dysfunction before th...

Roman A. Lukaszewski, Helen E. Jones, Vivian H. Gersuk… in Intensive Care Medicine (2022)

Article

The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute the simple solution. Author's reply

Daniel A. Hofmaenner, Mervyn Singer in Intensive Care Medicine (2022)

Article

Challenging management dogma where evidence is non-existent, weak or outdated

Medical practice is dogged by dogma. A conclusive evidence base is lacking for many aspects of patient management. Clinicians, therefore, rely upon engrained treatment strategies as the dogma seems to work, or...

Daniel A. Hofmaenner, Mervyn Singer in Intensive Care Medicine (2022)

Article

“L'histoire se répète”, one size does not fit all. Author’s reply

Timothy Arthur Chandos Snow, Naveed Saleem, Mervyn Singer… in Intensive Care Medicine (2021)

Article

Do not just sit there, do something … but do no harm: the worrying aspects of COVID-19 experimental interventions

Mervyn Singer, Andre Kalil in Intensive Care Medicine (2021)

Article

Tocilizumab in COVID-19: a meta-analysis, trial sequential analysis, and meta-regression of randomized-controlled trials

Interleukin-6 (IL-6) levels discriminate between patients with mild and severe COVID-19, making IL-6 inhibition an attractive therapeutic strategy. We conducted a systematic review, meta-analysis, trial sequen...

Timothy Arthur Chandos Snow, Naveed Saleem, Gareth Ambler… in Intensive Care Medicine (2021)

Article

Steroids in ARDS: more light is being shed

Nishkantha Arulkumaran, Timothy Arthur Chandos Snow… in Intensive Care Medicine (2020)

Article

Do critical care patients hibernate? Theoretical support for less is more

Giacomo Stanzani, Robert Tidswell, Mervyn Singer in Intensive Care Medicine (2020)

Article

Correction to: Impact on mortality of prompt admission to critical care for deteriorating ward patients: an instrumental variable analysis using critical care bed strain

This article was originally published under a CC BY-NC 4.0 license, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly.

Steve Harris, Mervyn Singer, Colin Sanderson, Richard Grieve… in Intensive Care Medicine (2018)

Article

Impact on mortality of prompt admission to critical care for deteriorating ward patients: an instrumental variable analysis using critical care bed strain

To estimate the effect of prompt admission to critical care on mortality for deteriorating ward patients.

Steve Harris, Mervyn Singer, Colin Sanderson, Richard Grieve… in Intensive Care Medicine (2018)

Article

Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)

The CIGMA study investigated a novel human polyclonal antibody preparation (trimodulin) containing ~ 23% immunoglobulin (Ig) M, ~ 21% IgA, and ~ 56% IgG as add-on therapy for patients with severe community-acq...

Tobias Welte, R. Phillip Dellinger, Henning Ebelt, Miguel Ferrer… in Intensive Care Medicine (2018)