19 Result(s)
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Article
Open AccessPrescribing practices of inhaled corticosteroids for premature infants in the neonatal intensive care unit
Despite limited safety and efficacy data, inhaled corticosteroids (ICS) are prescribed to premature infants in the neonatal intensive care unit (NICU). We examined contemporary use and risk factors for ICS use...
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Article
A phase I trial of caffeine to evaluate safety in infants with hypoxic-ischemic encephalopathy
Caffeine provides neuroprotection following hypoxic-ischemic injury in animals. We characterized the safety of escalating doses of caffeine in infants with hypoxic-ischemic encephalopathy (HIE) receiving thera...
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Article
Differential placental CpG methylation is associated with chronic lung disease of prematurity
Chronic lung disease (CLD) is the most common pulmonary morbidity in extremely preterm infants. It is unclear to what extent prenatal exposures influence the risk of CLD. Epigenetic variation in placenta DNA m...
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Article
Correction: Duration of noninvasive respiratory support and risk for bronchopulmonary dysplasia or death
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Article
Duration of noninvasive respiratory support and risk for bronchopulmonary dysplasia or death
To determine whether the duration of noninvasive respiratory support exposure is associated with bronchopulmonary dysplasia (BPD) or death in preterm infants.
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Article
Association between postmenstrual age and furosemide dosing practices in very preterm infants
Furosemide renal clearance is slow after very preterm (VP) birth and increases with postnatal maturation. We compared furosemide dose frequency and total daily dose between postmenstrual age (PMA) groups in VP...
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Article
Safety of sildenafil in extremely premature infants: a phase I trial
To characterize the safety of sildenafil in premature infants.
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Article
Vasoactive medications in extremely low gestational age neonates during the first postnatal week
The management of early hypotension in extremely low gestational age neonates (ELGANs) varies greatly between centers. The objective of this study was to provide updated data on the use of vasoactive medicatio...
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Article
Wide range of perioperative drugs and doses used in inguinal hernia repairs for premature infants
Characterize the types and doses of commonly administered perioperative drugs in inguinal hernia (IH) repair for premature infants.
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Article
Association of chorioamnionitis and patent ductus arteriosus in a national U.S. cohort
To estimate the effect of clinical chorioamnionitis on the risk of patent ductus arteriosus (PDA).
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Article
Open AccessSafety of sildenafil in premature infants with severe bronchopulmonary dysplasia (SILDI-SAFE): a multicenter, randomized, placebo-controlled, sequential dose-escalating, double-masked, safety study
Pulmonary hypertension is a deadly complication of bronchopulmonary dysplasia, the most common pulmonary morbidity of prematurity. Despite these catastrophic consequences, no evidence-based therapies are avail...
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Article
Outcomes associated with surfactant in more mature and larger premature infants with respiratory distress syndrome
Examine the effect of off-label surfactant on mortality and morbidity in more mature and larger premature infants diagnosed with respiratory distress syndrome (RDS).
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Article
Medication use in infants with severe bronchopulmonary dysplasia admitted to United States children’s hospitals
To identify the number of cumulative medication exposures and most frequently used medications in infants with severe BPD.
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Article
Open AccessCorrection to: Association between furosemide in premature infants and sensorineural hearing loss and nephrocalcinosis: a systematic review
Following publication of the original article [1], the authors notified us that they would like to acknowledge Anjali Gupta for her contribution to the background for this systematic review.
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Article
Agreement of an echocardiogram-based diagnosis of pulmonary hypertension in infants at risk for bronchopulmonary dysplasia among masked reviewers
To evaluate the agreement of an echocardiogram-based pulmonary hypertension diagnosis in premature infants at risk for bronchopulmonary dysplasia (BPD).
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Article
Open AccessAssociation between furosemide in premature infants and sensorineural hearing loss and nephrocalcinosis: a systematic review
Furosemide is a potent loop diuretic commonly and variably used by neonatologists to improve oxygenation and lung compliance in premature infants. There are several safety concerns with use of furosemide in pr...
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Article
Open AccessClinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study
Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Very different models using clinical parameters at an early postnatal age to predict BPD have been developed with little extensive qu...
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Article
Regional Variation in Late Preterm Births in North Carolina
Late preterm (LPT) neonates (34 0/7th–36 6/7th weeks’ gestation) account for 70% of all premature births in the United States. LPT neonates have a higher morbidity and mortality risk than term neonates. LPT bi...
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Article
Open AccessDevelopment of a proxy-reported pulmonary outcome scale for preterm infants with bronchopulmonary dysplasia
To develop an accurate, proxy-reported bedside measurement tool for assessment of the severity of bronchopulmonary dysplasia (also called chronic lung disease) in preterm infants to supplement providers' curre...
