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  1. No Access

    Article

    Cognitive analysis of metabolomics data for systems biology

    Cognitive computing is revolutionizing the way big data are processed and integrated, with artificial intelligence (AI) natural language processing (NLP) platforms hel** researchers to efficiently search and...

    Erica L.-W. Majumder, Elizabeth M. Billings, H. Paul Benton… in Nature Protocols (2021)

  2. Article

    Open Access

    The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells

    Histones modulate gene expression by chromatin compaction, regulating numerous processes such as differentiation. However, the mechanisms underlying histone degradation remain elusive. Human embryonic stem cel...

    Azra Fatima, Dilber Irmak, Alireza Noormohammadi… in Communications Biology (2020)

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    Article

    A molecular mechanism explaining albuminuria in kidney disease

    Mammalian kidneys constantly filter large amounts of liquid, with almost complete retention of albumin and other macromolecules in the plasma. Breakdown of the three-layered renal filtration barrier results in...

    Linus Butt, David Unnersjö-Jess, Martin Höhne, Aurelie Edwards… in Nature Metabolism (2020)

  4. No Access

    Article

    Identification of bioactive metabolites using activity metabolomics

    The metabolome, the collection of small-molecule chemical entities involved in metabolism, has traditionally been studied with the aim of identifying biomarkers in the diagnosis and prediction of disease. Howe...

    Markus M. Rinschen, Julijana Ivanisevic… in Nature Reviews Molecular Cell Biology (2019)