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  1. Article

    Open Access

    The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells

    Histones modulate gene expression by chromatin compaction, regulating numerous processes such as differentiation. However, the mechanisms underlying histone degradation remain elusive. Human embryonic stem cel...

    Azra Fatima, Dilber Irmak, Alireza Noormohammadi in Communications Biology (2020)

  2. Article

    Defining the General Principles of Stem Cell Aging: Lessons from Organismal Models

    One of the most obvious characteristics of the aging process is the progressive decline in the regenerative potential of tissues. Adult somatic stem cells are critical for rejuvenating tissues and persist thro...

    Seda Koyuncu, Dilber Irmak, Isabel Saez, David Vilchez in Current Stem Cell Reports (2015)