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  1. Article

    Open Access

    Clinical landscape of macrophage-reprogramming cancer immunotherapies

    Tumour-associated macrophages (TAMs) sustain a tumour-supporting and immunosuppressive milieu and therefore aggravate cancer prognosis. To modify TAM behaviour and unlock their anti-tumoural potential, novel T...

    Jenna H. Rannikko, Maija Hollmén in British Journal of Cancer (2024)

  2. Article

    Open Access

    New tools to prevent cancer growth and spread: a ‘Clever’ approach

    Clever-1 (also known as Stabilin-1 and FEEL-1) is a scavenger receptor expressed on lymphatic endothelial cells, sinusoidal endothelial cells and immunosuppressive monocytes and macrophages. Its role in cancer...

    Maija Hollmén, Carlos R. Figueiredo, Sirpa Jalkanen in British Journal of Cancer (2020)

  3. No Access

    Article

    Regulation of CD73 in the development of lower limb atherosclerosis

    Atherosclerosis is an inflammatory process of the arterial wall. CD73 (also known as ecto-5′-nucleotidase) is a key regulator of cell signaling in response to inflammation and hypoxia, and may be important in ...

    Juho Jalkanen, Maija Hollmén, Sirpa Jalkanen, Harri Hakovirta in Purinergic Signalling (2017)