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Article
Open AccessClinical landscape of macrophage-reprogramming cancer immunotherapies
Tumour-associated macrophages (TAMs) sustain a tumour-supporting and immunosuppressive milieu and therefore aggravate cancer prognosis. To modify TAM behaviour and unlock their anti-tumoural potential, novel T...
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Article
Open AccessNew tools to prevent cancer growth and spread: a ‘Clever’ approach
Clever-1 (also known as Stabilin-1 and FEEL-1) is a scavenger receptor expressed on lymphatic endothelial cells, sinusoidal endothelial cells and immunosuppressive monocytes and macrophages. Its role in cancer...
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Article
Regulation of CD73 in the development of lower limb atherosclerosis
Atherosclerosis is an inflammatory process of the arterial wall. CD73 (also known as ecto-5′-nucleotidase) is a key regulator of cell signaling in response to inflammation and hypoxia, and may be important in ...