25 Result(s)

Article

In search of new stratification strategies: tissue proteomic profiling of papillary thyroid microcarcinoma in patients with localized disease and lateral neck metastases

Papillary thyroid carcinomas (PTC) are the most common thyroid malignancies that are often diagnosed as microcarcinomas when the tumor is less than one centimetre in diameter. Currently, there are no valid str...

Filip Matovinovic, Rudjer Novak, Stela Hrkac… in Journal of Cancer Research and Clinical On… (2023)

Article

Clinical need for bone morphogenetic proteins

Slobodan Vukičević, Lovorka Grgurević, Marko Pećina in International Orthopaedics (2017)

Chapter

BMPs in Inflammation

Bone morphogenetic proteins are regulators of embryonic development with multiple functions in adult organs and tissues. Here we summarize effects of BMPs outside the musculoskeletal system, focused on their r...

Lovorka Grgurevic, Ivo Dumic-Cule… in Bone Morphogenetic Proteins: Systems Biolo… (2017)

Chapter

Osteogrow: A Novel Bone Graft Substitute for Orthopedic Reconstruction

Complications associated with the clinical use of BMP2 and BMP7 result from the limited understanding of their molecular mechanisms in bone remodeling. Recently, a novel BMP6-based approach has been developed ...

Lovorka Grgurevic, Igor Erjavec… in Bone Morphogenetic Proteins: Systems Biolo… (2017)

Chapter

Bone Morphogenetic Protein-7 and Its Role in Acute Kidney Injury and Chronic Kidney Failure

Bone morphogenetic protein (BMP)-7 is required for embryonic kidney development, plays a functional role in the adult kidney as renal hormone for vascular and skeletal integrity, and modulates calcium and phos...

Kuber T. Sampath, Lovorka Grgurevic… in Bone Morphogenetic Proteins: Systems Biolo… (2017)

Reference Work Entry In depth

Bone Morphogenetic Proteins in Inflammation

Slobodan Vukicevic, Lovorka Grgurevic in Compendium of Inflammatory Diseases (2016)

Article

Biological aspects of segmental bone defects management

Segmental bone defect management is among the most demanding issues in orthopaedics and there is a great medical need for establishing an appropriate treatment option. Tissue transfer, including bone autograft...

Ivo Dumic-Cule, Marko Pecina, Mislav Jelic, Morana Jankolija… in International Orthopaedics (2015)

Article

Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice

Iron overload accelerates bone loss in mice lacking the bone morphogenetic protein 6 (Bmp6) gene, which is the key endogenous regulator of hepcidin, iron homeostasis gene. We investigated involvement of other BMP...

Martina Pauk, Lovorka Grgurevic, Jelena Brkljacic… in International Orthopaedics (2015)

Reference Work Entry In depth

Scaffold-Free Endogenous Healing of the Articular Cartilage Lesion

The regeneration of the joint cartilage remains a major challenge in medicine, because the factors initiating cartilage formation, maturation, and healing are poorly understood. The ideal outcome of the joint ...

Mislav Jelic, Lovorka Grgurevic, Slobodan Vukicevic in Sports Injuries (2015)

Article

Dynamics of optic canal and orbital cavity development revealed by microCT

Numerous studies have attempted to clarify the exact anatomy and variations of the optic canal with non-conclusive results due to its close proximity to many vulnerable structures. We sought to determine the d...

Ivo Dumic-Cule, Domagoj Eljuga, Ali Izadpanah… in Surgical and Radiologic Anatomy (2014)

Article

Systemically available bone morphogenetic protein two and seven affect bone metabolism

Bone morphogenetic protein (BMP)-2 and -7 are used in patients with long-bone fractures, nonunions and spinal fusions. It is unknown whether their potential systemic bioavailability following local bone admini...

Ivo Dumic-Cule, Jelena Brkljacic, Dunja Rogic… in International Orthopaedics (2014)

Article

The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing

The purpose of this study was to revise the clinical use of commercial BMP2 (Infuse) and BMP7 (Osigraft) based bone devices and explore the mechanism of action and efficacy of low BMP6 doses in a novel whole b...

Slobodan Vukicevic, Hermann Oppermann, Donatella Verbanac… in International Orthopaedics (2014)

Living Reference Work Entry In depth

Scaffold-Free Endogenous Healing of the Articular Cartilage Lesion

The regeneration of the joint cartilage remains a major challenge in medicine, because the factors initiating cartilage formation, maturation, and healing are poorly understood. The ideal outcome of the joint ...

Mislav Jelic, Lovorka Grgurevic, Slobodan Vukicevic in Sports Injuries

Living Reference Work Entry In depth

Bone Morphogenetic Proteins in Inflammation

Slobodan Vukicevic, Lovorka Grgurevic in Encyclopedia of Inflammatory Diseases