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Article
Impact of Hair Transplantation on Quality of Life
Alopecia is defined as partial or complete hair loss. The most common form is androgenetic alopecia, which occurs in both men and women. Despite the nonsurgical options available for treatment, the only perman...
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Article
Open AccessHow young radiologists use contrast media and manage adverse reactions: an international survey
To collect real-world data about the knowledge and self-perception of young radiologists concerning the use of contrast media (CM) and the management of adverse drug reactions (ADR).
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Article
Open AccessBone morphogenetic protein 1.3 inhibition decreases scar formation and supports cardiomyocyte survival after myocardial infarction
Despite the high prevalence of ischemic heart diseases worldwide, no antibody-based treatment currently exists. Starting from the evidence that a specific isoform of the Bone Morphogenetic Protein 1 (BMP1.3) i...
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Article
Importance of shear-wave elastography in prediction of Achilles tendon rupture
It was demonstrated that about 6% of patients with a ruptured Achilles tendon experience the rupture of contralateral tendon in the future; the aim of this study was to estimate the risk for rupture of contral...
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Article
Magnitude dependent discordance in liver stiffness measurements using elastography point quantification with transient elastography as the reference test
To investigate diagnostic performance of point shear wave elastography by elastography point quantification (ElastPQ) for non-invasive assessment of liver fibrosis in patients with chronic liver diseases (CLD).
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Article
Open AccessA novel role of bone morphogenetic protein 6 (BMP6) in glucose homeostasis
Bone morphogenetic proteins (BMPs) are involved in the development and homeostasis of multiple organs and tissues. There has been a significant focus on understanding the role of BMPs in pancreatic β-cell dysf...
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Article
Open AccessBone morphogenetic proteins in fracture repair
Bone fractures represent a significant medical morbidity among aged population with osteoporosis. Bone morphogenetic proteins (BMPs) are suggested to have therapeutic potential to enhance fracture healing in s...
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Chapter
BMPs in Inflammation
Bone morphogenetic proteins are regulators of embryonic development with multiple functions in adult organs and tissues. Here we summarize effects of BMPs outside the musculoskeletal system, focused on their r...
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Chapter
Osteogrow: A Novel Bone Graft Substitute for Orthopedic Reconstruction
Complications associated with the clinical use of BMP2 and BMP7 result from the limited understanding of their molecular mechanisms in bone remodeling. Recently, a novel BMP6-based approach has been developed ...
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Article
Biological aspects of segmental bone defects management
Segmental bone defect management is among the most demanding issues in orthopaedics and there is a great medical need for establishing an appropriate treatment option. Tissue transfer, including bone autograft...
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Article
Dynamics of optic canal and orbital cavity development revealed by microCT
Numerous studies have attempted to clarify the exact anatomy and variations of the optic canal with non-conclusive results due to its close proximity to many vulnerable structures. We sought to determine the d...
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Article
Systemically available bone morphogenetic protein two and seven affect bone metabolism
Bone morphogenetic protein (BMP)-2 and -7 are used in patients with long-bone fractures, nonunions and spinal fusions. It is unknown whether their potential systemic bioavailability following local bone admini...
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Article
The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing
The purpose of this study was to revise the clinical use of commercial BMP2 (Infuse) and BMP7 (Osigraft) based bone devices and explore the mechanism of action and efficacy of low BMP6 doses in a novel whole b...
