614 Result(s)
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Open AccessCTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment
The three-dimensional genome structure organized by CTCF is required for development. Clinically identified mutations in CTCF have been linked to adverse developmental outcomes. Nevertheless, the underlying mecha...
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Open AccessGiant nonlinear Hall and wireless rectification effects at room temperature in the elemental semiconductor tellurium
The second-order nonlinear Hall effect (NLHE) in non-centrosymmetric materials has recently drawn intense interest, since its inherent rectification could enable various device applications such as energy harv...
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Open AccessMultiple myeloma incidence and mortality trends in the United States, 1999–2020
Multiple myeloma (MM) is a plasma cell disorder accounting for approximately 10% of hematologic malignancies. There is limited epidemiological evidence regarding the long-term trends and disparities in MM in t...
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Open AccessMechanical properties and acoustic emission characteristics of mixed granite after different numbers of freeze‒thaw cycles
The mechanical properties of rocks in cold regions undergo significant changes as a result of decades of freeze‒thaw cycles with seasonal variations, which can lead to a series of geological disasters, such as...
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Open AccessCombined short-term and long-term emission controls improve air quality sustainably in China
The effectiveness of national policies for air pollution control has been demonstrated, but the relative effectiveness of short-term emission reduction measures in comparison with national policies has not. He...
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Open AccessChromosome-level genome assembly of the cottony cushion scale Icerya purchasi
The cottony cushion scale, Icerya purchasi, a polyphagous pest, poses a significant threat to the global citrus industry. The hermaphroditic self-fertilization observed in I. purchasi is an exceptionally rare rep...
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Open AccessEnhancing computer image recognition with improved image algorithms
Advances in computer image recognition have significantly impacted many industries, including healthcare, security and autonomous systems. This paper aims to explore the potential of improving image algorithms...
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Open AccessHeterogeneous associations of multiplexed environmental factors and multidimensional aging metrics
Complicated associations between multiplexed environmental factors and aging are poorly understood. We manipulated aging using multidimensional metrics such as phenotypic age, brain age, and brain volumes in t...
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Open AccessSkin-inspired, sensory robots for electronic implants
Drawing inspiration from cohesive integration of skeletal muscles and sensory skins in vertebrate animals, we present a design strategy of soft robots, primarily consisting of an electronic skin (e-skin) and a...
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Open AccessA Bacillus velezensis strain isolated from oats with disease-preventing and growth-promoting properties
Endophytes have been shown to promote plant growth and health. In the present study, a Bacillus velezensis CH1 (CH1) strain was isolated and identified from high-quality oats, which was capable of producing indol...
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Open AccessNutrient levels control root growth responses to high ambient temperature in plants
Global warming will lead to significantly increased temperatures on earth. Plants respond to high ambient temperature with altered developmental and growth programs, termed thermomorphogenesis. Here we show th...
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Open AccessObservation of the photonic Hall effect and photonic magnetoresistance in random lasers
Modulation of scattering in random lasers (RLs) by magnetic fields has attracted much attention due to its rich physical insights. We fabricate magnetic gain polymer optical fiber to generate RLs. From macrosc...
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Open AccessGenomic characterization reveals distinct mutational landscapes and therapeutic implications between different molecular subtypes of triple-negative breast cancer
Triple-negative breast cancer (TNBC) has high heterogeneity, poor prognosis, and limited treatment success. Recently, an immunohistochemistry-based surrogate classification for the “Fudan University Shanghai C...
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Open AccessA protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions
Protein ubiquitination regulates a wide range of cellular processes. The degree of protein ubiquitination is determined by the delicate balance between ubiquitin ligase (E3)-mediated ubiquitination and deubiqu...
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Open AccessABA-mediated regulation of rice grain quality and seed dormancy via the NF-YB1-SLRL2-bHLH144 Module
Abscisic acid (ABA) plays a crucial role in promoting plant stress resistance and seed dormancy. However, how ABA regulates rice quality remains unclear. This study identifies a key transcription factor SLR1-l...
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Open AccessPricing, assembly rate optimizations and coordination for prefabricated construction supply chain with government subsidies
Prefabricated construction, a sustainable construction method, has become the inevitable trend for the future development of the construction industry. The subsidy policies for prefabricated construction enter...
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Open AccessSustainable thermal regulation improves stability and efficiency in all-perovskite tandem solar cells
Mixed Sn-Pb perovskites have emerged as promising photovoltaic materials for both single- and multi-junction solar cells. However, achieving their scale-up and practical application requires further enhancemen...
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Open AccessTRIM25 predominately associates with anti-viral stress granules
Stress granules (SGs) are induced by various environmental stressors, resulting in their compositional and functional heterogeneity. SGs play a crucial role in the antiviral process, owing to their potent tran...
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Open AccessOptimal obesity- and lipid-related indices for predicting type 2 diabetes in middle-aged and elderly Chinese
To investigate the screening and predicting functions of obesity- and lipid-related indices for type 2 diabetes (T2D) in middle-aged and elderly Chinese, as well as the ideal predicted cut-off value. This stud...
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Open AccessDe novo transcriptome assembly database for 100 tissues from each of seven species of domestic herbivore
Domesticated herbivores are an important agricultural resource that play a critical role in global food security, particularly as they can adapt to varied environments, including marginal lands. An understandi...