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  1. Article

    Open Access

    ABA-mediated regulation of rice grain quality and seed dormancy via the NF-YB1-SLRL2-bHLH144 Module

    Abscisic acid (ABA) plays a crucial role in promoting plant stress resistance and seed dormancy. However, how ABA regulates rice quality remains unclear. This study identifies a key transcription factor SLR1-l...

    **-Dong Wang, **g Wang, Li-Chun Huang, Li-Jun Kan, Chu-**n Wang in Nature Communications (2024)

  2. Article

    Open Access

    RGA1 regulates grain size, rice quality and seed germination in the small and round grain mutant srg5

    Generating elite rice varieties with high yield and superior quality is the main goal of rice breeding programs. Key agronomic traits, including grain size and seed germination characteristics, affect the fina...

    **a Yang, Jun Lu, Wu-Jian Shi, Yu-Hao Chen, Jia-Wen Yu, Sai-Hua Chen in BMC Plant Biology (2024)

  3. Article

    Open Access

    Antiproliferative and apoptotic effects of telmisartan in human glioma cells

    Glioblastoma is the most common primary central nervous system tumor in adults. Angiotensin II receptor blockers (ARBs) are broadly applied to treat hypertension. Moreover, research has revealed that ARBs have...

    Yung-Lung Chang, Chung-Hsing Chou, Yao-Feng Li, Li-Chun Huang in Cancer Cell International (2023)

  4. Article

    Open Access

    Correction to: YAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma

    Yi-Zih Kuo, Ya-Rong Kang, Wei-Lun Chang, Lydia Chin Ling Sim in Cellular Oncology (2022)

  5. Article

    Open Access

    YAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma

    Although YAP1 and TAZ are believed to be equivalent downstream effectors of the Hippo pathway, differential expression of YAP1 or TAZ suggests distinct functions during cancer progression. The exact role of YA...

    Yi-Zih Kuo, Ya-Rong Kang, Wei-Lun Chang, Lydia Chin-Ling Sim in Cellular Oncology (2022)

  6. Article

    Open Access

    Shugoshin 2 is a biomarker for pathological grading and survival prediction in patients with gliomas

    Glioblastomas are the most common type of adult primary brain neoplasms. Clinically, it is helpful to identify biomarkers to predict the survival of patients with gliomas due to its poor outcome. Shugoshin 2 (SGO...

    Ying Kao, Wen-Chiuan Tsai, Ssu-Han Chen, Shao-Yuan Hsu, Li-Chun Huang in Scientific Reports (2021)

  7. No Access

    Article

    Overexpression of Cell-Surface Marker SLC16A1 Shortened Survival in Human High-Grade Gliomas

    Solute carrier family 16 member 1 (SLC16A1) is a crucial transcription factor in modifying cancer progression and metastasis. However, its character in defining the clinical prognosis of human gliomas has not ...

    Hong-Han Lin, Wen-Chiuan Tsai, Chia-Kuang Tsai in Journal of Molecular Neuroscience (2021)

  8. No Access

    Article

    Modulation of ARTS and XIAP by Parkin Is Associated with Carnosic Acid Protects SH-SY5Y Cells against 6-Hydroxydopamine-Induced Apoptosis

    The mediation of apoptosis-related protein in the TGF-β signaling pathway (ARTS) and X-liked inhibitor of apoptosis protein (XIAP) by parkin plays a critical role in preventing Parkinson’s disease. We studied ...

    Ru-Huei Fu, Li-Chun Huang, Chia-Yuan Lin, Chia-Wen Tsai in Molecular Neurobiology (2018)

  9. Article

    Open Access

    Dissection of brassinosteroid-regulated proteins in rice embryos during germination by quantitative proteomics

    Brassinosteroids (BRs), essential plant-specific steroidal hormones, function in a wide spectrum of plant growth and development events, including seed germination. Rice is not only a monocotyledonous model pl...

    Qian-Feng Li, Min **ong, Peng Xu, Li-Chun Huang, Chang-Quan Zhang in Scientific Reports (2016)

  10. Article

    Open Access

    The effect of red light and far-red light conditions on secondary metabolism in Agarwood

    Agarwood, a heartwood derived from Aquilaria trees, is a valuable commodity that has seen prevalent use among many cultures. In particular, it is widely used in herbal medicine and many compounds in agarwood are ...

    Tony Chien-Yen Kuo, Chuan-Hung Chen, Shu-Hwa Chen, I-Hsuan Lu in BMC Plant Biology (2015)

  11. Article

    Open Access

    Identification of cucurbitacins and assembly of a draft genome for Aquilaria agallocha

    Agarwood is derived from Aquilaria trees, the trade of which has come under strict control with a listing in Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora. ...

    Chuan-Hung Chen, Tony Chien-Yen Kuo, Meng-Han Yang, Ting-Ying Chien in BMC Genomics (2014)

  12. Article

    Open Access

    EMMPRIN expression positively correlates with WHO grades of astrocytomas and meningiomas

    High-grade primary brain tumors possessed poor outcome due to invasiveness. Extracellular matrix metalloproteinase inducer (EMMPRIN) stimulates peri-tumoral fibroblasts to secrete matrix metalloproteinase and ...

    Wen-Chiuan Tsai, Ying Chen, Li-Chun Huang, Herng-Sheng Lee in Journal of Neuro-Oncology (2013)

  13. No Access

    Article

    Examining user satisfaction of school nursing information system in Taiwan

    Information technology applications in healthcare have existed for more than three decades, methods to evaluate outputs and outcomes in healthcare are still to remain a challenge for decision makers. The adopt...

    Chun-Po Yin, Hsiu-Chia Ko, Li-Chun Huang, Fan-Chuan Tseng in Health and Technology (2012)

  14. Article

    Open Access

    Proteomic profiling of proteins associated with the rejuvenation of Sequoia sempervirens (D. Don) Endl

    Restoration of rooting competence is important for rejuvenation in Sequoia sempervirens (D. Don) Endl and is achieved by repeatedly grafting Sequoia shoots after 16 and 30 years of cultivation in vitro.

    Ing-Feng Chang, Peng-Jen Chen, Chin-Hui Shen, Tsung-Ju Hsieh in Proteome Science (2010)

  15. No Access

    Article

    Allocating the costs of multi-purpose water resource development: a case study of Chi-Chi Weir in Taiwan

    Most multi-purpose water resources have been planned and constructed by governments in Taiwan to meet the water demands of different users. However, economic and solvency differences among parties using water ...

    Li-Chun Huang, Ching-Kai Hsiao, Sheng-Feng Kuo in Paddy and Water Environment (2009)

  16. No Access

    Article

    Extended flower longevity of Petunia hybrida plants transformed with boers, a mutated ERS gene of Brassica oleracea

    Petunia x hybridaHort.Vilm.-Andr. was transformed with boers, a mutatedallele of BOERS, an ethylene receptor sensor gene ofBrassica oleracea.boers was obtained by removing anEcoRI cutting site with a silent muta...

    Jei-Fu Shaw, Hsiu-Hui Chen, Mei-Fong Tsai, Ching-I Kuo, Li-Chun Huang in Molecular Breeding (2002)

  17. No Access

    Article

    High polyphenol oxidase activity and low titratable acidity in browning bamboo tissue culture

    Tissue browning that frequently results in the early death of bamboo shoots in vitro correlated directly with polyphenol oxidase (PPO, EC 1.10.3.1) activity and inversely with titratable acidity. It was unrelated...

    Li-Chun Huang, Ya-Lin Lee, Bau-Lian Huang in In Vitro Cellular & Developmental Biology … (2002)

  18. No Access

    Article

    Develo** an improved In vitro propagation system for slow-growing species using garcinia mangostana L. (mangosteen)

    This investigation disclosed that evaluation of tissue culture parameters of slowly develo** species (e.g. Garcinia mangostana) requires monitoring of treatments through two or more successive, relatively long ...

    Li-Chun Huang, Bau-Liang Huang in In Vitro Cellular & Developmental Biology … (2000)

  19. No Access

    Article

    A micropropagation protocol forCinnamomum camphora

    A micropropagation protocol was developed forCinnamomum camphora (L.) Sieb., using as initial explants 3–5-mm shoot tips from newly emerged laterals of 2-yr-old trees. Performance of small shoot tips was compared...

    Li-Chun Huang, Bau-Liang Huang in In Vitro Cellular & Developmental Biology … (1998)

  20. No Access

    Chapter

    Cell Cycle Control of Genetic Stability

    Boveri’s deduction that genetic instability is involved in the initiation of tumorigenesis remains one of the most insightful in tumor biology (Boveri, T., 1914). It is remarkable that it came as an extrapolat...

    Geoffrey M. Wahl, Steven P. Linke in Genomic Instability and Immortality in Can… (1997)

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