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Article
Open AccessGenomic characterization reveals distinct mutational landscapes and therapeutic implications between different molecular subtypes of triple-negative breast cancer
Triple-negative breast cancer (TNBC) has high heterogeneity, poor prognosis, and limited treatment success. Recently, an immunohistochemistry-based surrogate classification for the “Fudan University Shanghai C...
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Article
Comparison of PD-L1 expression and MMR status between primary and matched metastatic lesions in patients with cervical cancer
Programmed death-ligand 1 (PD-L1) and DNA mismatch repair (MMR) are considered predictive biomarkers for immunotherapy in cervical cancer. However, their expression in primary tumors and metastases does not al...
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Article
Subclassifying triple-negative breast cancers and its potential clinical utility
The molecular subty** of triple-negative breast cancer (TNBC) is critical to guiding individualized patient treatment. In this study, we sought to characterize the clinicopathologic features of TNBC subtypes...
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Article
Open AccessSecretory breast carcinoma in a female adult with liver metastsis: a case report and literature review
Secretory breast carcinoma is an uncommon subset of breast cancer that usually has a favorable outcome. Although initially described in children, it also occurs in adults where it may metastasize, possibly res...
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Article
Experimental Study on Axial Compression of Concrete with Initial Crack under Hydrostatic Pressure
The axial compression test of concrete with different initial cracks under hydrostatic pressure is carried out. The fracture propagation is analyzed based on the bearing state as well as the apparent phenomena...
