![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessMechanism and bioinformatics analysis of the effect of berberine-enhanced fluconazole against drug-resistant Candida albicans
Biofilms produced by Candida albicans present a challenge in treatment with antifungal drug. Enhancing the sensitivity to fluconazole (FLC) is a reasonable method for treating FLC-resistant species. Moreover, sev...
-
Article
Open AccessThe effect of white grub (Maladera Verticalis) larvae feeding on rhizosphere microbial characterization of aerobic rice (Oryza sativa L.) in Puer City, Yunnan Province, China
Rhizosphere microorganisms are vital in plants’ growth and development and these beneficial microbes are recruited to the root-zone soil when experiencing various environmental stresses. However, the effect of...
-
Article
Open AccessHPV-associated cervicovaginal microbiome and host metabolome characteristics
Cervicovaginal microbiome plays an important role in the persistence of HPV infection and subsequent disease development. However, cervicovaginal microbiota varied cross populations with different habits and r...
-
Article
Open AccessTranscriptomic and physiological analyses of Trichoderma citrinoviride HT-1 assisted phytoremediation of Cd contaminated water by Phragmites australis
Plant growth promoting microbe assisted phytoremediation is considered a more effective approach to rehabilitation than the single use of plants, but underlying mechanism is still unclear. In this study, we co...
-
Article
Open AccessST218 Klebsiella pneumoniae became a high-risk clone for multidrug resistance and hypervirulence
The occurrence of multidrug-resistant and hypervirulent Klebsiella pneumoniae (MDR-hvKp) worldwide poses a great challenge for public health. Few studies have focused on ST218 MDR-hvKp.
-
Article
Open AccessMolecular epidemiology of Mycoplasma pneumoniae pneumonia in children, Wuhan, 2020–2022
Mycoplasma pneumoniae (M. pneumoniae) is an important pathogen of community-acquired pneumonia in children. The factors contributing to the severity of illness caused by M. pneumoniae infection are still under in...
-
Article
Open AccessDiversity and functional prediction of fungal communities in different segments of mongolian horse gastrointestinal tracts
Anaerobic fungi are effective fibre-degrading microorganisms in the digestive tract of horses. However, our understanding of their diversity and community structure is limited, especially in different parts of...
-
Article
Open AccessGenomic and metabonomic methods reveal the probiotic functions of swine-derived Ligilactobacillus salivarius
As substitutes for antibiotics, probiotic bacteria protect against digestive infections caused by pathogenic bacteria. Ligilactobacillus salivarius is a species of native lactobacillus found in both humans and an...
-
Article
Open AccessStructure and ecological function of the soil microbiome associated with ‘Sanghuang’ mushrooms suffering from fungal diseases
The most serious challenges in medicinal ‘Sanghuang’ mushroom production are the fungal diseases caused by various molds. Application of biological agents has been regarded as a potential crop disease manageme...
-
Article
Open AccessNew native Bacillus thuringiensis strains induce high insecticidal action against Culex pipiens pallens larvae and adults
Mosquitoes of many species are key disease vectors, killing millions of people each year. Bacillus thuringiensis-based insecticide formulations are largely recognized as among the most effective, ecologically saf...
-
Article
Open AccessLocal characteristics of molecular epidemiolgy of Acinetobacter baumannii in Jilin province (northeast China)
A. Baumannii is an opportunistic nosocomial pathogen which has severe antibiotic resistance. However, the epidemiology is less clearly understood in Jilin province and China. Thus, 89 A. baumannii isolates from a...
-
Article
Open AccessBacteriomes in lesions of pulmonary tuberculosis and its association with status of Mycobacterium tuberculosis excretion
Bacteria in lung play an important role in sustaining lung health. Understanding the characteristics of bacteriomes in lesions of pulmonary tuberculosis (TB) patients, who excrete Mycobacterium tuberculosis (MTB)...
-
Article
Open AccessInactivation of the MSTN gene expression changes the composition and function of the gut microbiome in sheep
Myostatin (MSTN) negatively regulates the muscle growth in animals and MSTN deficient sheep have been widely reported previously. The goal of this study was to explore how MSTN inactivation influences their gut m...
-
Article
Open AccessAge-dependent variations in rumen bacterial community of Mongolian cattle from weaning to adulthood
Rumen microbes play an important role in ruminant energy supply and animal performance. Previous studies showed that the rumen microbiome of Mongolian cattle has adapted to degrade the rough forage to provide ...
-
Article
Open AccessMechanisms of linezolid resistance in Staphylococcus capitis with the novel mutation C2128T in the 23S rRNA gene in China
The objective of this study was to investigate the molecular characteristics and potential resistance mechanisms of linezolid-resistant (LZR) Staphylococcus capitis isolates from a tertiary hospital in China.
-
Article
Open AccessProfiling the role of microorganisms in quality improvement of the aged flue-cured tobacco
The aging process in the tobacco production, as in other food industries, is an important process for improving the quality of raw materials. In the spontaneous aging, the complex components in flue-cured toba...
-
Article
Open AccessChitin-rich heteroglycan from Sporothrix schenckii sensu stricto potentiates fungal clearance in a mouse model of sporotrichosis and promotes macrophages phagocytosis
Fungal cell wall polysaccharides maintain the integrity of fungi and interact with host immune cells. The immunomodulation of fungal polysaccharides has been demonstrated in previous studies. However, the effe...
-
Article
Open AccessStructural insights into acyl-ACP selective recognition by the Aeromonas hydrophila AHL synthase AhyI
Aeromonas hydrophila is a gram-negative bacterium and the major causative agent of the fish disease motile aeromonad septicemia (MAS). It uses N-acyl-homoserine lactone (AHL) quorum sensing signals to coordinate ...
-
Article
Open AccessLactobacillus rhamnosus HDB1258 modulates gut microbiota-mediated immune response in mice with or without lipopolysaccharide-induced systemic inflammation
Gut microbiota closely communicate in the immune system to maintain a balanced immune homeostasis in the gastrointestinal tract of the host. Oral administration of probiotics modulates gut microbiota compositi...
-
Article
Open AccessmRNA-Seq reveals the quorum sensing system luxS gene contributes to the environmental fitness of Streptococcus suis type 2
Streptococcus suis type 2 (SS2) is an important zoonotic pathogen. We have previously reported the structure of LuxS protein and found that the luxS gene is closely related to biofilm, virulence gene expression a...