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  1. No Access

    Chapter and Conference Paper

    Multimeric Coactivator Complexes for Steroid/Nuclear Receptors

    Nuclear receptors regulate transcription in direct response to their cognate hormonal ligands. Ligand-binding leads to the dissociation of corepressors and the recruitment of coactivators. Many of these factor...

    L. P. Freedman in Testicular Tangrams (2002)

  2. No Access

    Article

    Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

    Two crystal structures of the glucocorticoid receptor DNA-binding domain complexed with DNA are reported. The domain has a globular fold which contains two Zn-nucleated substructures of distinct conformation a...

    B. F. Luisi, W. X. Xu, Z. Otwinowski, L. P. Freedman, K. R. Yamamoto… in Nature (1991)