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  1. No Access

    Article

    An affective disorder in zebrafish with mutation of the glucocorticoid receptor

    Upon binding of cortisol, the glucocorticoid receptor (GR) regulates the transcription of specific target genes, including those that encode the stress hormones corticotropin-releasing hormone (CRH) and adreno...

    L Ziv, A Muto, P J Schoonheim, S H Meijsing, D Strasser… in Molecular Psychiatry (2013)

  2. No Access

    Article

    Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

    Two crystal structures of the glucocorticoid receptor DNA-binding domain complexed with DNA are reported. The domain has a globular fold which contains two Zn-nucleated substructures of distinct conformation a...

    B. F. Luisi, W. X. Xu, Z. Otwinowski, L. P. Freedman, K. R. Yamamoto… in Nature (1991)

  3. No Access

    Article

    Photo-CIDNP study of the interaction between the glucocorticoid receptor DNA-binding domain and glucocorticoid response elements

    Photo-CIDNP studies were performed on two protein fragments that both contain the double zinc-finger DNA-binding domain of the glucocorticoid receptor. In the absence of DNA, Tyr452 and Tyr474 are polarised in bo...

    E. Kellenbach, T. Härd, R. Boelens, K. Dahlman… in Journal of Biomolecular NMR (1991)