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  1. No Access

    Article

    Melatonin Stimulates Epithelium Migration in Wound Models In Vitro and In Vivo

    We studied the effect of bovine brain gangliosides, individual ganglioside GM1, and melatonin on the rate of wound closure under in vitro conditions and the effect of melatonin on the rate of wound healing under

    E. A. Vorotelyak, L. A. Malchenko… in Bulletin of Experimental Biology and Medic… (2019)

  2. No Access

    Article

    Glutamic Acid Signal Synchronizes Protein Synthesis Kinetics in Hepatocytes from Old Rats for the Following Several Days. Cell Metabolism Memory

    The kinetics of protein synthesis was investigated in primary cultures of hepatocytes from old rats in serum–free medium. The rats were fed mixed fodder supplemented with glutamic acid and then transferred to ...

    V. Y. Brodsky, L. A. Malchenko, D. S. Lazarev, N. N. Butorina… in Biochemistry (Moscow) (2018)

  3. No Access

    Article

    Glutamic acid as enhancer of protein synthesis kinetics in hepatocytes from old rats

    Dense cultures of hepatocytes from old rats (~2 years old, body weight 530-610 g) are different from similar cultures of hepatocytes from young rats by the low amplitude of protein synthesis rhythm. Addition o...

    V. Y. Brodsky, L. A. Malchenko, N. N. Butorina… in Biochemistry (Moscow) (2017)

  4. No Access

    Article

    Glutamic acid – amino acid, neurotransmitter, and drug – is responsible for protein synthesis rhythm in hepatocyte populations in vitro and in vivo

    Primary cultures of rat hepatocytes were studied in serum-free media. Ultradian protein synthesis rhythm was used as a marker of cell synchronization in the population. Addition of glutamic acid (0.2 mg/ml) to...

    V. Y. Brodsky, L. A. Malchenko, D. S. Konchenko, N. D. Zvezdina… in Biochemistry (Moscow) (2016)

  5. No Access

    Article

    Effect of Protein Synthesis Rhythm-Organizing Signal Persists for a Day after Single Administration of Melatonin to Rat

    Melatonin administered to rat intraperitoneally organizes ultradian rhythm of protein synthesis in hepatocytes that persists for 1 day after exposure to the synchronizing signal. Hepatocytes were isolated 1 da...

    N. D. Zvezdina, L. A. Malchenko… in Bulletin of Experimental Biology and Medic… (2014)