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Article
Endogenous Regeneration of Alveolar Bone by Decellularized Tooth Matrix
The efficiency of bone tissue regeneration by decellularized tooth matrix, demineralized tooth matrix, and commercial xenograft Bio-Oss Spongiosa was compared on the model of a critical-size circular defect in...
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Article
Mesenchymal Stromal Cell-Derived Extracellular Vesicles: Their Features and Impact on Fibrosis and Myogenesis in Vitro
Extracellular vesicles (EVs) and, particularly, exosomes are becoming a promising material for “cell-free therapy” of many pathologic conditions. In the recent years therapeutic effects of mesenchymal stromal ...
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Article
The Myogenic Potential of Mesenchymal Stromal Cells and Their Effect on Skeletal Muscle Regeneration
The participation of mesenchymal stromal cells (MSCs) in the regeneration of muscle tissue was analyzed. It is shown that rat bone marrow MSCs do not show potency for myogenic differentiation in vitro under th...
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Article
Osteogenic Potential of Decellularized Tooth Matrix
We studied the possibility of using decellularized tooth matrix as a scaffold to restore bone tissue. It was found that mesenchymal stem cells underwent spontaneous osteogenic differentiation on the decellular...
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Article
Experimental Study of the Possibility of Culturing of Mesenchymal Stromal Cell and Induction of Osteogenic Differentiation on Collagen-Based Scaffolds of Various Modifications
We analyzed the suitability of various collagen-based scaffolds for culturing and osteogenic differentiation of mesenchymal stromal cells (MSC). Decellularized and lyophilized swine intestinal submucosa (SIS) ...
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Article
The Administration of Semax and HLDF-6 Peptides to Rats Regulates Protein Synthesis Rhythm in Hepatocytes and Corrects Senescent Disturbances
To clarify the organizing effect of Semax and HLDF-6 peptides on the kinetics of protein synthesis in hepatocytes, in addition to an in vitro study (Brodsky et al., 2019), the effects of these peptides in vivo...
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Article
Melatonin Stimulates Epithelium Migration in Wound Models In Vitro and In Vivo
We studied the effect of bovine brain gangliosides, individual ganglioside GM1, and melatonin on the rate of wound closure under in vitro conditions and the effect of melatonin on the rate of wound healing under
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Article
Neuroprotective Peptides Regulate Protein-Synthesis Kinetics in Hepatocytes of Different Age Rats
In the search for stable factors regulating direct cell–cell interactions and effects on the properties of cells in aging organisms, the regulatory peptides Semax and HLDF-6 were studied. The circahoralian rhy...
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Article
Effect of Mesenchymal Stromal Cells and Conditioned Media on Healing of Skin Wound
We studied the effect of mesenchymal stromal cells and conditioned media on healing of full-thickness skin wound in rats. Cell transplantation to the wound bed did not accelerate wound closing and had no effec...
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Article
Glutamic Acid Signal Synchronizes Protein Synthesis Kinetics in Hepatocytes from Old Rats for the Following Several Days. Cell Metabolism Memory
The kinetics of protein synthesis was investigated in primary cultures of hepatocytes from old rats in serum–free medium. The rats were fed mixed fodder supplemented with glutamic acid and then transferred to ...
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Article
Glutamic acid as enhancer of protein synthesis kinetics in hepatocytes from old rats
Dense cultures of hepatocytes from old rats (~2 years old, body weight 530-610 g) are different from similar cultures of hepatocytes from young rats by the low amplitude of protein synthesis rhythm. Addition o...
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Article
Comparative study of bone marrow mesenchymal stromal cells at different stages of ontogeny
The aim of this study was to analyze the changes that occur in the population of bone marrow mesenchymal stromal cells (MSCs) during the individual development of an organism. For this purpose, the basic chara...
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Article
World collections of parasitic worms
This article provides information about the depositories of parasitic worms in the scientific institutes and museums in the United States, Japan, and Europe (the total number of samples and the availability of...
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Article
Comparative analysis of subpopulations of mesenchymal stromal cells of the bone marrow and fetal liver differing in sensitivity to 5-fluorouracil
It is shown that the effect of 5-fluorouracil (5-FU) on mesenchymal stromal cells (MSCs) of the bone marrow and fetal liver of the rat enriches the population with cells with a reduced proliferative potential....
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Article
Mesenchymal Stromal Cells of Rat Spleen during Pre-and Postnatal Ontogeny: Comparative Analysis of Clonal Growth, Phenotype and Differentiation Potencies
Comparison of mesenchymal stromal cells of embryonic and adult rat spleen showed that splenic cells from 20-day rat fetuses exhibit the capacity for clonal growth, express surface antigens CD73, CD90, and CD10...
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Article
Clonal growth, phenotype, and differentiation potential of mesenchymal stromal cells derived from the rat fetal bone
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Article
Cell Composition of the Primary Culture of Fetal Liver
Fetal liver is known as a source of multipotent mesenchymal stromal cells. These cells are routinely isolated by adhesion to plastic, but thus prepared culture is contaminated by other cells. For instance, pri...
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Article
Clonal growth and differentiation of mesenchymal stromal cells from rat liver at different stages of embryogenesis
Fetal liver, during its hematopoietic activity, contains mesenchymal stromal cells (MSCs) generating its hematopoietic microenvironment. These cells are clonogenic and capable of multilineage differentiation; ...
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Article
Spontaneous and induced myogenesis in cell cultures from rat fetal liver
Fetal liver stroma consists of different cell populations. We found that the liver of 17- and 20-day rat fetuses contained skeletal muscle precursors that expressed MyoD. In primary cultures of liver cells fro...
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Article
Influence of primary adhesive interactions with fibronectin on clonal growth and osteogenic potential of rat mesenchymal stromal cells
Interactions with the extracellular matrix play an important role in the regulation of cell growth and differentiation. Fibronectin (Fn) is a major component of the extracellular matrix. The impact of Fn and i...
