16 Result(s)

Article

Cost-effectiveness of two online interventions supporting self-care for eczema for parents/carers and young people

To estimate the cost-effectiveness of online behavioral interventions (EczemaCareOnline.org.uk) designed to support eczema self-care management for parents/carers and young people from an NHS perspective.

Tracey H. Sach, Mary Onoja, Holly Clarke… in The European Journal of Health Economics (2024)

Article

A practical guide to implementing a successful social media recruitment strategy: lessons from the Eczema Monitoring Online trial

Participant recruitment into clinical trials remains challenging. The global increase in the number of social media users has accelerated the use of social media as a modality of recruitment, particularly duri...

Arabella Baker, Eleanor J. Mitchell, Kim S. Thomas in Trials (2022)

Article

Feasibility of weekly participant-reported data collection in a pragmatic randomised controlled trial in primary care: experiences from the BATHE trial (Bath Additives for the Treatment of cHildhood Eczema)

Patient-reported outcomes measures in clinical trials ensure that evaluations of effectiveness focus on outcomes that are important to patients. In relapsing-remitting conditions, such as eczema, repeated meas...

Beth Stuart, Kate Rumsby, Miriam Santer, Matthew J. Ridd, Nick A. Francis… in Trials (2018)

Article

Effectiveness and cost-effectiveness of daily all-over-body application of emollient during the first year of life for preventing atopic eczema in high-risk children (The BEEP trial): protocol for a randomised controlled trial

Atopic eczema (AE) is a common skin problem that impairs quality of life and is associated with the development of other atopic diseases including asthma, food allergy and allergic rhinitis. AE treatment is a ...

Joanne R. Chalmers, Rachel H. Haines, Eleanor J. Mitchell, Kim S. Thomas… in Trials (2017)

Article

Investigating the effect of independent, blinded digital image assessment on the STOP GAP trial

Blinding is the process of kee** treatment assignment hidden and is used to minimise the possibility of bias. Trials at high risk of bias have been shown to report larger treatment effects than low-risk stud...

Emily Patsko, Peter J. Godolphin, Kim S. Thomas, Trish Hepburn… in Trials (2017)

Article

Systemic therapy for vulval Erosive Lichen Planus (the ‘hELP’ trial): study protocol for a randomised controlled trial

Erosive lichen planus affecting the vulva (ELPV) is a relatively rare, chronic condition causing painful raw areas in the vulvovaginal region. Symptoms are pain and burning, which impact upon daily living. The...

Rosalind C. Simpson, Ruth Murphy, Daniel J. Bratton, Matthew R. Sydes… in Trials (2016)

Article

Using existing trial data to inform the development of core outcome sets and improve efficiencies in research

Kim S Thomas, Lucy Bradshaw, Alan A Montgommery, Nick A Francis, Matthew J Ridd… in Trials (2015)

Article

A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial

Eczema is a chronic, itchy skin condition that can have a large impact on the quality of life of patients and their families. People with eczema are often keen to try out non-pharmacological therapies like sil...

Eleanor F. Harrison, Rachel H. Haines, Fiona Cowdell, Tracey H. Sach… in Trials (2015)

Article

Achieving consensus over the assessment of clinical signs in eczema trials

Kim S Thomas, Jochen Schmitt, Phyllis I Spuls, Eric Simpson, Masutaka Furue… in Trials (2015)

Article

Validation of the global resource of eczema trials (GREAT database)

Eczema (syn. Atopic Eczema or Atopic Dermatitis) is a chronic, relapsing, itchy skin condition which probably results from a combination of genetic and environmental factors. The Global Resource of EczemA Tria...

Helen Nankervis, Alison Devine, Hywel C Williams, John R Ingram… in BMC Dermatology (2015)

Article

Survey and online discussion groups to develop a patient-rated outcome measure on acceptability of treatment response in vitiligo

Vitiligo is a chronic depigmenting skin disorder which affects around 0.5-1% of the world’s population. The outcome measures used most commonly in trials to judge treatment success focus on repigmentation. Pat...

Selina K Tour, Kim S Thomas, Dawn-Marie Walker, Paul Leighton… in BMC Dermatology (2014)

Article

UK Dermatology Clinical Trials Network’s STOP GAP trial (a multicentre trial of prednisolone versus ciclosporin for pyoderma gangrenosum): protocol for a randomised controlled trial

Pyoderma gangrenosum (PG) is a rare inflammatory skin disorder characterised by painful and rapidly progressing skin ulceration. PG can be extremely difficult to treat and patients often require systemic immun...

Fiona F Craig, Kim S Thomas, Eleanor J Mitchell, Hywel C Williams, John Norrie… in Trials (2012)

Article

The UK clinical research network - has it been a success for dermatology clinical trials?

Following the successful introduction of five topic-specific research networks in the UK, the Comprehensive Local Research Network (CLRN) was established in 2008 in order to provide a blanket level of support ...

Kim S Thomas, Karin Koller, Katharine Foster, Jo Perdue, Lisa Charlesworth… in Trials (2011)

Article

Studying a disease with no home - lessons in trial recruitment from the PATCH II study

Cellulitis is a very common condition that often recurs. The PATCH II study was designed to explore the possibility of preventing future episodes of cellulitis, with resultant cost savings for the NHS. This wa...

Kim S Thomas in Trials (2010)

Article

Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg

This paper describes the results of a feasibility study for a randomised controlled trial (RCT).

Kim S Thomas, Neil H Cox, Boki SP Savelyich, Debbie Shipley, Sarah Meredith… in Trials (2007)