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Article
The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that affects approximately 0.3–6 out of every 100,000 people worldwide. Clinical trials are scarce but there is growing interest in using newer and m...
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Reference Work Entry In depth
Age, Frailty, and Impaired Wound Healing
Chronic wounds in older individuals are among the most devastating and difficult to treat age-related ailments and are strongly intertwined with a sense of self-worth and quality of life. As the population age...
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Living Reference Work Entry In depth
Age, Frailty and Impaired Wound Healing
Chronic wounds in older individuals are among the most devastating and difficult to treat age-related ailments and are strongly intertwined with a sense of self-worth and quality of life. As the population age...
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Article
Consequences of age on ischemic wound healing in rats: altered antioxidant activity and delayed wound closure
Advertisements targeted at the elderly population suggest that antioxidant therapy will reduce free radicals and promote wound healing, yet few scientific studies substantiate these claims. To better understan...
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Article
Method to analyze collagenase and gelatinase activity by fibroblasts in culture
The net amount of collagen produced and deposited by fibroblasts in cell culture is determined by the rate of collagen synthesis as well as the rate of collagen degradation. Although collagen synthesis can be ...
