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Open AccessPhysical activity and eating behaviors patterns associated with high blood pressure among Chinese children and adolescents
Physical activity and eating behavior are associated with hypertension in children and adolescents. Revealing the associations between physical activity patterns, eating behavior patterns and high blood pressu...
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Article
Open AccessMiR-196b-3p and miR-450b-3p are key regulators of adipogenesis in porcine intramuscular and subcutaneous adipocytes
As components of white adipose tissue, porcine intramuscular (IM) and subcutaneous (SC) adipocytes undergo similar differentiation and adipogenesis processes. However, the adipogenic capacity of IM adipocytes ...
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Open AccessCloning and functional verification of a porcine adipose tissue-specific promoter
Fat deposition is an important economic trait in pigs. In the past decades, many genes regulating porcine fat deposition were identified by Omics technology and verified by cell biology studies. Using genetica...
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Open AccessSelf-reported sleep characteristics associated with dementia among rural-dwelling Chinese older adults: a population-based study
Sleep characteristics associated with dementia are poorly defined and whether their associations vary by demographics and APOE genotype among older adults are unclear.
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Open AccessHuatan Dingji Decoction intervening in atrial fibrillation: protocol for a randomized double-blind single-simulated placebo-controlled clinical trial
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and can lead to heart failure (HF), stroke, pulmonary embolism (PE), and other complications, seriously affecting people’s quality of life...
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Open AccessPrognostic value of the extent of lymphadenectomy for esophageal cancer-specific survival among T1 patients
Clinically, there are no clear guidelines on the extent of lymphadenectomy in patients with T1 esophageal cancer. Studying the minimum number of lymph nodes for resection may increase cancer-specific survival.
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Open AccessGlobal profiling of distinct cysteine redox forms reveals wide-ranging redox regulation in C. elegans
Post-translational changes in the redox state of cysteine residues can rapidly and reversibly alter protein functions, thereby modulating biological processes. The nematode C. elegans is an ideal model organism f...
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Article
Open AccessRisk factors for severe COVID-19 in middle-aged patients without comorbidities: a multicentre retrospective study
Information regarding characteristics and risk factors of COVID-19 amongst middle-aged (40–59 years) patients without comorbidities is scarce.
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Open AccessEvaluation of TaqMan Array card (TAC) for the detection of 28 respiratory pathogens
Respiratory infections are a serious threat to human health. So, rapid detection of all respiratory pathogens can facilitate prompt treatment and prevent the deterioration of respiratory disease. Previously pu...
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Open AccessIdentification and characterization a novel polar tube protein (NbPTP6) from the microsporidian Nosema bombycis
Microsporidians are opportunistic pathogens with a wide range of hosts, including invertebrates, vertebrates and even humans. Microsporidians possess a highly specialized invasion structure, the polar tube. Wh...
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Open AccessVisual and anatomic outcomes of sustained single agent anti-VEGF treatment versus double anti-VEGF switching in the treatment of persistent diabetic macular edema
To compare the anatomical and visual outcomes in eyes with persistent diabetic macular edema (DME) after initial anti-VEGF therapy that were retreated continuously with the same anti-VEGF drug versus those tha...
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Open AccessMorphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography
To examine the baseline morphological characteristics and alterations in intraretinal microvascular abnormalities (IRMAs) in response to anti-vascular endothelial growth factor (anti-VEGF) treatment, documente...
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Open AccessClimate factors driven typhus group rickettsiosis incidence dynamics in **shuangbanna Dai autonomous prefecture of Yunnan province in China, 2005–2017
Typhus group rickettsiosis (TGR), which is a neglected vector-borne infectious disease, including epidemic typhus and endemic typhus. We explored the lag effects and nonlinear association between meteorologica...
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Open AccessThe driver of dengue fever incidence in two high-risk areas of China: A comparative study
In China, the knowledge of the underlying causes of heterogeneous distribution pattern of dengue fever in different high-risk areas is limited. A comparative study will help us understand the influencing facto...
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Open AccessA novel ABA functional analogue B2 enhances drought tolerance in wheat
Drought stress negatively affects wheat growth and yield. Application of drought agent is an effective way to improve crop drought tolerance, therefore increasing crop yield. Based on the structure of abscisic...
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Open AccessSuilysin-induced Platelet-Neutrophil Complexes Formation is Triggered by Pore Formation-dependent Calcium Influx
Platelet activation and platelet–neutrophil interactions have been found to be involved in inflammation, organ failure and soft-tissue necrosis in bacterial infections. Streptococcus suis, an emerging human patho...
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Open AccessPhenol-soluble modulin α4 mediates Staphylococcus aureus-associated vascular leakage by stimulating heparin-binding protein release from neutrophils
Vascular leakage frequently occurs in patients with severe Staphylococcus aureus infection. However, the mechanism underlying S. aureus infection-induced vascular leakage remains unclear. Here, we identified the
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Open AccessDrechslerella stenobrocha genome illustrates the mechanism of constricting rings and the origin of nematode predation in fungi
Nematode-trap** fungi are a unique group of organisms that can capture nematodes using sophisticated trap** structures. The genome of Drechslerella stenobrocha, a constricting-ring-forming fungus, has been se...
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How carnivorous fungi use three-celled constricting rings to trap nematodes
Predacious fungi form specialized hyphae structures to trap nematodes and other microscopic animals. Among the six kinds of trap** devices, the constricting ring is the only one that actively captures nemato...
