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Article
Open AccessInitiating PeriCBD to probe perinatal influences on neurodevelopment during 3–10 years in China
Adverse perinatal factors can interfere with the normal development of the brain, potentially resulting in long-term effects on the comprehensive development of children. Presently, the understanding of cognit...
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Article
L-RCap: RNN-capsule model via label semantics for MLTC
Multi-label text classification attempts to assign a label set to one specific document, which is more closely related to real life. Network models based on traditional deep learning achieve good prediction re...
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Article
Smaller and efficient mobile network design for image classification
The classic inverted residual block has been used in the design of existing lightweight neural network models, but it still has a large number of parameters and calculations, and there is room for improvement ...
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Article
Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient-sensing pathways
Compounds with lifespan extension activity are rare, although increasing research efforts have been invested in this field to find ways to extend healthy lifespan. By applying a yeast-based high-throughput ass...
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Article
Unsupervised image clustering algorithm based on contrastive learning and K-nearest neighbors
With the development of the times, people generate a huge amount of data every day, most of which are unlabeled data, but manual labeling needs a lot of time and effort, so unsupervised algorithms are being us...
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Article
LAANet: lightweight attention-guided asymmetric network for real-time semantic segmentation
With the increasing demand for real-world scenarios such as robot navigation and autonomous driving, how to achieve a good trade-off between segmentation accuracy, inference speed and model size has become a c...
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Article
Real-time detector design for small targets based on bi-channel feature fusion mechanism
YOLOv4-tiny is a simplified version of YOLOv4 detector, which is extremely fast and with few parameters. However, the detection performance of YOLOv4-tiny is poor while the recognition of small targets and occ...
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Article
Open AccessGlobal profiling of distinct cysteine redox forms reveals wide-ranging redox regulation in C. elegans
Post-translational changes in the redox state of cysteine residues can rapidly and reversibly alter protein functions, thereby modulating biological processes. The nematode C. elegans is an ideal model organism f...
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Article
Open AccessMitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways
The mitochondrial unfolded protein response (mitoUPR) is a stress response pathway activated by disruption of proteostasis in the mitochondria. This pathway has been proposed to influence lifespan, with studie...
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Article
Tanshinones extend chronological lifespan in budding yeast Saccharomyces cerevisiae
Natural products with anti-aging property have drawn great attention recently but examples of such compounds are exceedingly scarce. By applying a high-throughput assay based on yeast chronological lifespan me...